Evidence map›Paper›PMID 34308793›Full record

ArticleGlobal health action2021

Neonatal mortality rates, characteristics, and risk factors for neonatal deaths in Ghana: analyses of data from two health and demographic surveillance systems.

Shadrach Dare, Abraham R Oduro, Seth Owusu-Agyei, Daniel F Mackay, Laurence Gruer, Alfred Kwesi Manyeh, Ernest Nettey, James F Phillips, Kwaku Poku Asante, Paul Welaga and 1 more

Open access · goldAbstract read
In one paragraph

Article in Global health action, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
9.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 3 countries.

Shadrach DareMother and Infant Research Unit, School of Health Sciences, University of Dundee, Dundee, UK.ORCID 0000-0002-2528-5263
Abraham R OduroNavrongo Health Research Centre, Ghana Health Service, Navrongo, Ghana.ORCID 0000-0002-4191-7419
Seth Owusu-AgyeiKintampo Health Research Centre, Ghana Health Service, Kintampo, Ghana.ORCID 0000-0002-0807-1781
Daniel F MackayInstitute of Health and Wellbeing, University of Glasgow, Glasgow, UK.
Laurence GruerInstitute of Health and Wellbeing, University of Glasgow, Glasgow, UK.ORCID 0000-0002-1089-2896
Alfred Kwesi ManyehInstitute of Health Research, University of Health and Allied Sciences, Ho, Ghana.ORCID 0000-0002-7005-5707
Ernest NetteyKintampo Health Research Centre, Ghana Health Service, Kintampo, Ghana.
James F PhillipsMailman School of Public Health, Columbia University, New York, NY, USA.ORCID 0000-0002-6720-7204
Kwaku Poku AsanteKintampo Health Research Centre, Ghana Health Service, Kintampo, Ghana.
Paul WelagaNavrongo Health Research Centre, Ghana Health Service, Navrongo, Ghana.
Jill P PellMother and Infant Research Unit, School of Health Sciences, University of Dundee, Dundee, UK.ORCID 0000-0002-8898-7035
Kintampo Health Research Centre · GHNavrongo Health Research Centre · GHUniversity of Dundee · GBUniversity of Glasgow · GBUniversity of Health and Allied Sciences · GHColumbia University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundReducing neonatal mortality rates (NMR) in developing countries is a key global health goal, but weak registration systems in the region stifle public health efforts.

objectiveTo calculate NMRs, investigate modifiable risk factors, and explore neonatal deaths by place of birth and death, and cause of death in two administrative areas in Ghana.

methodsData on livebirths were extracted from the health and demographic surveillance systems in Navrongo (2004-2012) and Kintampo (2005-2010). Cause of death was determined from neonatal verbal autopsy forms. Univariable and multivariable logistic regression were used to analyse factors associated with neonatal death. Multiple imputations were used to address missing data.

resultsThe overall NMR was 18.8 in Navrongo (17,016 live births, 320 deaths) and 12.5 in Kintampo (11,207 live births, 140 deaths). The annual NMR declined in both areas. 54.7% of the births occurred in health facilities. 70.9% of deaths occurred in the first week. The main causes of death were infection (NMR 4.3), asphyxia (NMR 3.7) and prematurity (NMR 2.2). The risk of death was higher among hospital births than home births: Navrongo (adjusted OR 1.14, 95% CI: 1.03-1.25, p = 0.01); Kintampo (adjusted OR 1.76, 95% CI: 1.55-2.00, p < 0.01). However, a majority of deaths occurred at home (Navrongo 61.3%; Kintampo 50.7%). Among hospital births dying in hospital, the leading cause of death was asphyxia; among hospital and home births dying at home, it was infection.

conclusionThe NMR in these two areas of Ghana reduced over time. Preventing deaths by asphyxia and infection should be prioritised, centred respectively on improving post-delivery care in health facilities and subsequent post-natal care at home.

Indexed as

Perinatal DeathCause of DeathGhanaHumansInfant MortalityInfant, NewbornRisk Factorscause of deathchild healthGhanaNeonatal mortality raterisk factors

Identifiers

PMID34308793
PMCPMC8317945
OpenAlexW3185010741

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.