Evidence map›Paper›PMID 34308786›Full record

ReviewGlobal health action2021

Syndemic contexts: findings from a review of research on non-communicable diseases and interviews with experts.

Irene Pirrone, Marjolein Dieleman, Ria Reis, Christopher Pell

Abstract readReview
In one paragraph

Review in Global health action, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  9. A comprehensive vision for women's mental health.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2025
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  18. COVID-19, Mental Health, and Chronic Illnesses: A Syndemic Perspective.International journal of environmental research and public health · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Irene PirroneFaculty of Science, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Marjolein DielemanFaculty of Science, Athena Institute, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.ORCID 0000-0001-8399-7114
Ria ReisDepartment of Public Health and Primary Care, Leiden University Medical Centre, Leiden, The Netherlands.
Christopher PellAmsterdam Institute for Global Health and Development, Amsterdam, The Netherlands.ORCID 0000-0001-9405-5851

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSyndemics are characterized by the clustering of two or more health conditions, their adverse interaction, and contextual factors that create the conditions for clustering and/or interaction that worsens health outcomes. Studying syndemics entails drawing on diverse disciplines, including epidemiology and anthropology. This often means collaboration between researchers with different scholarly backgrounds, who share and - ideally - integrate their findings.

objectiveThis article examines how context within syndemics has been defined and studied.

methodsA literature review of empirical studies focusing on syndemics involving non-communicable diseases (NCDs) and mental health conditions was conducted and the full text of 13 articles was analyzed. The review was followed-up with semi-structured interviews with 11 expert researchers working in the field.

resultsThe review and interviews highlighted a relatively consistent definition of syndemics. The reviewed studies of NCD-related syndemics tended to focus on micro-level context, suggesting a need to analyze further underlying structural factors. In their syndemics research, respondents described working with other disciplines and, although there were some challenges, welcomed greater disciplinary diversity. Methodological gaps, including a lack of mixed methods and longitudinal studies, were identified, for which further interdisciplinary collaborations would be beneficial.

conclusionsNCD-related syndemics research would benefit from further analysis of structural factors and the interconnections between syndemic components across multiple levels, together with more ambitious research designs integrating quantitative and qualitative methods. Research on the COVID-19 pandemic can benefit from a syndemics approach, particularly to understand vulnerability and the unequal impacts of this public health crisis.

Indexed as

COVID-19Noncommunicable DiseasesHumansPandemicsSARS-CoV-2SyndemicconceptualisationcontextinterdisciplinaritymethodologySyndemics

Identifiers

PMID34308786
PMCPMC8317915

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.