Evidence map›Paper›PMID 34308605›Full record

ArticleTurkish journal of haematology : official journal of Turkish Society of Haematology2021

Convalescent Plasma Reduces Endogenous Antibody Response in COVID-19: A Retrospective Cross-Sectional Study

Ahmet Omma, Abdulsamet Erden, Serdar Can Güven, İhsan Ateş, Orhan Küçükşahin

Abstract read
In one paragraph

Article in Turkish journal of haematology : official journal of Turkish Society of Haematology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ahmet OmmaMinistry of Health Ankara City Hospital, Department of Internal Medicine, Division of Rheumatology, Ankara, TurkeyORCID 0000-0003-2582-7445
Abdulsamet ErdenMinistry of Health Ankara City Hospital, Department of Internal Medicine, Division of Rheumatology, Ankara, TurkeyORCID 0000-0002-8084-2018
Serdar Can GüvenMinistry of Health Ankara City Hospital, Department of Internal Medicine, Division of Rheumatology, Ankara, TurkeyORCID 0000-0003-1965-9756
İhsan AteşMinistry of Health Ankara City Hospital, Department of Internal Medicine, Ankara, Turkey
Orhan KüçükşahinYıldırım Bayezıt University Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Ankara, Turkey

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The aim of this study is to investigate post-COVID-19 antibody titers in patients who received convalescent plasma (CP) in addition to standard-of-care treatment. Materials and Methods: Hospitalized COVID-19 patients who received CP in addition to standard care were retrospectively investigated. Patients who received CP with a recorded total COVID-19 antibody test result after treatment were included. From among hospitalized COVID-19 patients who received only standard care with a recorded total COVID-19 antibody test result, a control group matched for age, gender, and comorbidities was formed. Total COVID-19 antibody index levels were compared. Results: Thirty-three CP recipients were enrolled in the study. The control group consisted of 34 age-, gender-, and comorbidity-matched standard-care patients. Median total COVID-19 antibody index levels were significantly reduced in the CP group. Conclusion: Although CP therapy may have benefits for disease outcome, its potential ability to hamper long-term immunity may be a problem.

Indexed as

AdultAgedAged, 80 and overAntibody FormationCase-Control StudiesCOVID-19COVID-19 SerotherapyCross-Sectional StudiesFemaleHospitalizationHumansImmunization, PassiveMaleMiddle AgedRetrospective StudiesSARS-CoV-2AntibodyConvalescent plasmaCOVID-19Immunity

Identifiers

PMID34308605
PMCPMC8656133

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.