ArticleEClinicalMedicine2021
Vitamin D status in Mainland of China: A systematic review and meta-analysis.
Article in EClinicalMedicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 6 of them syntheses that pooled it.
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Who cites it
37 citing papers in PubMed, 6 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- A systematic review and meta-analysis of circulating 25-hydroxyvitamin D concentration and vitamin D status worldwide.Journal of public health (Oxford, England) · 2025Pooled it
- Vitamin D levels and its influencing factors in children and adolescents in mainland China: a systematic review and meta-analysis.BMJ open · 2025Pooled it
- Maternal hypertensive disorders during pregnancy and their link to childhood asthma: a systematic review and meta-analysis.Frontiers in pediatrics · 2025Pooled it
- Pooled it
- Global and regional prevalence of vitamin D deficiency in population-based studies from 2000 to 2022: A pooled analysis of 7.9 million participants.Frontiers in nutrition · 2023Pooled it
- Vitamin D insufficiency is high in Malaysia: A systematic review and meta-analysis of studies on vitamin D status in Malaysia.Frontiers in nutrition · 2022Pooled it
- Effect of vitamin DJournal of the International Society of Sports Nutrition · 2023Trial
- Muscle-Related Effect of Whey Protein and Vitamin DNutrients · 2022Trial
- Knowledge, attitudes, and practices regarding vitamin D among university students in Quzhou, China: a cross-sectional study.Annals of medicine · 2026Article
- Vitamin D and Health: Establishing Causal Relationships Through Observational Evidence and Hill's Criteria in a Biological Framework.Nutrients · 2026Review
- Effects of Age, Season, and Pregnancy History on Vitamin D Status in Women Seeking Preconception Care.Medical science monitor : international medical journal of experimental and clinical research · 2026Article
- Vitamin D deficiency among apparently healthy adults in northern China: behavioral correlates and an indoor-lifestyle framework.Frontiers in public health · 2026Article
- High burden of vitamin D deficiency in Chinese university students: impact of sun protection culture.Frontiers in nutrition · 2026Article
- Intervention methods and influencing factors of vitamin D deficiency in Northeast China: a self-controlled trial and randomized controlled trial study.Frontiers in nutrition · 2026Article
- A decade-long assessment reveals persistent vitamin D deficiency and its associated factors in early-pregnant women from northern China (2016-2025).Frontiers in nutrition · 2026Article
- Prevalence and correlates of vitamin D deficiency in a mixed-age hospital-based cohort.Frontiers in public health · 2026Article
- Associations of umbilical cord vitamin D levels with childhood cardiometabolic risks: a longitudinal mother-child study.Frontiers in nutrition · 2026Article
- Article
- Vitamin Status and Risk of Age-Related Diseases Among Adult Residents of the Pearl River Delta Region.Nutrients · 2025Article
- Assessment of vitamin D nutritional status among adults in Lu'an, China, based on serum 25-hydroxyvitamin D measured by LC-MS/MS.Frontiers in nutrition · 2025Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLow vitamin D (VitD) status is becoming a global health issue. Previous heterogenous results are urging a meta-analysis to delineate a panorama of VitD conditions in the general population in Mainland of China.
methodsWe performed a systematic review and meta-analysis by searching PubMed, Web of Science, EMBASE, China National Knowledge Infrastructure, WanFang, and VIP databases up to June 4, 2021. The inclusion criteria were as follows: (1) original articles or dissertations focused on VitD status of people in Mainland of China; and (2) studies were population-based, cross-sectional, or longitudinal cohort with baseline data. The outcomes were serum 25(OH)D concentration and the prevalence of low VitD status. Low VitD status included VitD deficiency (< 30 nmol/L) and VitD inadequacy (< 50 nmol/L). Data were estimated by Hierarchical Bayesian methods. All included studies were cross-sectional or longitudinal cohort studies about VitD status of people in Mainland of China. (Registration: PROSPERO CRD42021226130).
findingsA total of 105 eligible studies including 234,519 subjects were included. In adults, the overall mean 25(OH)D concentration was 44.3 nmol/L (95% Credible Interval [CrI]: 39.8-48.7). The pooled prevalence of VitD deficiency and inadequacy was 20.7% (95% CrI: 11.9-32.9) and 63.2% (95% CrI: 53.5-72.3), respectively. In children and adolescents, the overall mean 25(OH)D concentration was 52.2 nmol/L (95% CrI: 46.7-57.5). The pooled prevalence of VitD deficiency and inadequacy was 23.0% (95% CrI: 8.9-44.3) and 46.8% (95% CrI: 37.2-56.6), respectively. Specially, we identified that the prevalence of VitD inadequacy increased with age in populations with age ≤ 18 years and ≥ 60 years.
interpretationLow VitD status is prominent in general population of Mainland of China, especially for adults.
fundingNational Major Scientific and Technological Special Project for "Significant New Drugs Development" (2017ZX09304022).
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Registered trials
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