Evidence map›Paper›PMID 34308317›Full record

ArticleEClinicalMedicine2021

A systematic review and meta-analysis of gestational diabetes mellitus and mental health among BAME populations.

Gayathri Delanerolle, Peter Phiri, Yutian Zeng, Kathleen Marston, Nicola Tempest, Paula Busuulwa, Ashish Shetty, William Goodison, Hemananda Muniraman, Georgia Duffy and 8 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in EClinicalMedicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07003503 (Explore the Risk Factors for Antenatal Mental Disorders in Pregnant Women With Hyperglycemia), which is not on this map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07003503 not yet recruitingnot on this mapstarted 2025, after this paper: background citation

Explore the Risk Factors for Antenatal Mental Disorders in Pregnant Women With Hyperglycemia

TypeobservationalSponsorShenzhen Hospital of Southern Medical UniversityRan2025 to 2026Enrolled635ConditionsHyperglycemia, Mental Disorder, Pregnancy Complications
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Pooled it
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  13. [Exploring the Causal Relationship Between Coagulation Function and Gestational Diabetes Mellitus Through Mendelian Randomization].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024
    Article
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  16. The NDDG criteria versus the IADPSG or the ADA criteria for diagnosing early-onset gestational diabetes mellitus or abnormal glucose tolerance.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 2 countries.

Gayathri DelanerolleOxford Brain Health Clinical Trials Unit, University of Oxford, United Kingdom.
Peter PhiriSouthern Health NHS Foundation Trust, United Kingdom.
Yutian ZengSouthern University of Science and Technology, United Kingdom.
Kathleen MarstonUniversity of Liverpool, United Kingdom.
Nicola TempestUniversity of Liverpool, United Kingdom.
Paula BusuulwaUniversity of Liverpool, United Kingdom.
Ashish ShettyUniversity College London Hospitals NHS Foundation Trust, United Kingdom.
William GoodisonUniversity College London Hospitals NHS Foundation Trust, United Kingdom.
Hemananda MuniramanDepartment of Pediatrics, Creighton University Medical School, United Kingdom.
Georgia DuffyUniversity of Liverpool, United Kingdom.
Kathryn ElliotSouthern Health NHS Foundation Trust, United Kingdom.
Alison MacleanUniversity of Liverpool, United Kingdom.
Kingshuk MajumderUniversity of Manchester NHS Foundation Trust, United Kingdom.
Martin HirschUniversity College London Hospitals NHS Foundation Trust, United Kingdom.
Shanaya RathodSouthern Health NHS Foundation Trust, United Kingdom.
Vanessa RaymontDepartment of Psychiatry, University of Oxford, United Kingdom.
Jian Qing ShiSouthern University of Science and Technology, United Kingdom.
Dharani K HapangamaUniversity of Liverpool, United Kingdom.
University of Liverpool · GBSouthern Health NHS Foundation Trust · GBUniversity College London Hospitals NHS Foundation Trust · GBSouthern University of Science and Technology · CNUniversity of Oxford · GBUniversity of Manchester · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGestational diabetes mellitus (GDM) is a common complication of pregnancy and is associated with an increased risk of mental health (MH) disorders including antenatal and postnatal depression (PND), anxiety and post-traumatic-stress-disorder (PTSD). We hypothesized GDM and MH disorders will disproportionately affect individuals from Black, Asian and Minority Ethnic backgrounds.

methodsA systematic methodology was developed, and a protocol was published in PROSPERO (CRD42020210863) and a systematic review of publications between 1st January 1990 and 30th January 2021 was conducted. Multiple electronic databases were explored using keywords and MeSH terms. The finalised dataset was analysed using statistical methods such as random-effect models, subgroup analysis and sensitivity analysis. These were used to determine odds ratio (OR) and 95% confidence intervals (CI) to establish prevalence using variables of PND, anxiety, PTSD and stress to name a few.

findingsSixty studies were finalised from the 20,040 data pool. Forty-six studies were included systematically with 14 used to meta-analyze GDM and MH outcomes. A second meta-analysis was conducted using 7 studies to determine GDM risk among Black, Asian and Minority Ethnic women with pre-existing MH disorders. The results indicate an increased risk with pooled adjusted OR for both reflected at 1.23, 95% CI of 1.00-1.50 and 1.29, 95% CI of 1.11-1.50 respectively.

interpretationThe available studies suggest a MH sequalae with GDM as well as a sequalae of GDM with MH among Black, Asian and Minority Ethnic populations. Our findings warrant further future exploration to better manage these patients.

fundingNot applicable.

Indexed as

BAMEGestational diabetes mellitusMental HealthWomen's Health and Wellbeing

Identifiers

PMID34308317
PMCPMC8283332
OpenAlexW3182072031

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.