Evidence map›Paper›PMID 34308272›Full record

ArticleIJU case reports2021

Improvement of urinary symptoms after bladder biopsy: A case of pathologically proven allergy-related cystitis during administration of nivolumab.

Shugo Yajima, Yasukazu Nakanishi, Shunya Matsumoto, Kenji Tanabe, Masato Sugano, Hitoshi Masuda

Open access · goldAbstract readCase Reports
In one paragraph

Article in IJU case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. [Immune Checkpoint Inhibitors Related Cystoureteritis:
A Case Report and Literature Review].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2023
    Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Shugo YajimaNational Cancer Center Hospital East Kashiwa, Chiba Japan.ORCID https://orcid.org/0000-0003-2300-8446
Yasukazu NakanishiNational Cancer Center Hospital East Kashiwa, Chiba Japan.
Shunya MatsumotoNational Cancer Center Hospital East Kashiwa, Chiba Japan.
Kenji TanabeNational Cancer Center Hospital East Kashiwa, Chiba Japan.
Masato SuganoNational Cancer Center Hospital East Kashiwa, Chiba Japan.
Hitoshi MasudaNational Cancer Center Hospital East Kashiwa, Chiba Japan.
National Cancer Center Hospital East · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWe present a case of cystitis, which was considered to be an immune-related adverse event associated with nivolumab administration. CASE PRESENTATION: A 47-year-old man suffered from sudden onset urinary symptoms after 18 cycles of nivolumab treatment for stage IV pulmonary adenocarcinoma. Urine culture and urine cytology were both negative. The symptoms were inferred to be related to nivolumab administration, and a bladder biopsy under spinal anesthesia was performed. The histopathological examination showed the evidence of allergic-related cystitis. We planned to administer corticosteroids, but the urinary symptoms disappeared after the bladder biopsy. Nivolumab treatment was continued without recurrent bladder symptoms.

conclusionWe reported a case of cystitis after treatment with nivolumab, which served as a reminder to consider the possibility of immune-related adverse events as a potential cause for any symptoms that develop during treatment with immuno-oncology drugs.

Indexed as

adverse drug eventcystitislung neoplasmsnivolumaburinary bladder

Identifiers

PMID34308272
PMCPMC8294138
OpenAlexW3138920341

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.