Evidence map›Paper›PMID 34308269›Full record

ArticleAnnual review of biomedical data science2019

Scientific Discovery Games for Biomedical Research.

Rhiju Das, Benjamin Keep, Peter Washington, Ingmar H Riedel-Kruse

Abstract read
In one paragraph

Article in Annual review of biomedical data science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Crowdsourced RNA design discovers diverse, reversible, efficient, self-contained molecular switches.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rhiju DasDepartment of Biochemistry and Department of Physics, Stanford University, Stanford, California 94305, USA.
Benjamin KeepDepartment of Learning Sciences, Stanford University, Stanford, California 94305, USA.
Peter WashingtonDepartment of Bioengineering, Stanford University, Stanford, California 94305, USA.
Ingmar H Riedel-KruseDepartment of Bioengineering, Stanford University, Stanford, California 94305, USA.

Funding

Next-generation computational/chemical methods for complex RNA structuresR35GM122579 · NIGMS · STANFORD UNIVERSITY · PI Rhiju Das · 2017 to 2026
$7.2M
NIGMS NIH HHS R35 GM122579
6 · The paper itself

Abstract

Over the past decade, scientific discovery games (SDGs) have emerged as a viable approach for biomedical research, engaging hundreds of thousands of volunteer players and resulting in numerous scientific publications. After describing the origins of this novel research approach, we review the scientific output of SDGs across molecular modeling, sequence alignment, neuroscience, pathology, cellular biology, genomics, and human cognition. We find compelling results and technical innovations arising in problem-oriented games such as Foldit and Eterna and in data-oriented games such as EyeWire and Project Discovery. We discuss emergent properties of player communities shared across different projects, including the diversity of communities and the extraordinary contributions of some volunteers, such as paper writing. Finally, we highlight connections to artificial intelligence, biological cloud laboratories, new game genres, science education, and open science that may drive the next generation of SDGs.

Indexed as

citizen sciencecloud laboratorycrowdsourcinginteractive mediascientific discovery gamesvideo games

Identifiers

PMID34308269
PMCPMC8297398

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.