Evidence map›Paper›PMID 34308231›Full record

ArticleThe East African health research journal2020

Feasibility of SMS to remind pregnant and breastfeeding women living with HIV to take antiretroviral treatment in Kilimanjaro region, Tanzania: a pilot study.

Kennedy M Ngowi, Eusebious Maro, Rob E Aarnoutse, Blandina T Mmbaga, Mirjam A G Sprangers, Peter Reiss, Pythia T Nieuwkerk, I Marion Sumari-de Boer

Open access · diamondAbstract read
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Article in The East African health research journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Kennedy M NgowiKilimanjaro Clinical Research Institute, Moshi, Tanzania, United Republic of.
Eusebious MaroKilimanjaro Christian Medical Center, Moshi, Tanzania, United Republic of.
Rob E AarnoutseRadboudumc, Radboud Institute for Health Sciences & Department of Pharmacy, Nijmegen, The Netherlands.
Blandina T MmbagaKilimanjaro Clinical Research Institute, Moshi, Tanzania, United Republic of.
Mirjam A G SprangersAmsterdam UMC, Location AMC, University of Amsterdam, Department of MedicalPsychology, Amsterdam, The Netherlands.
Peter ReissAmsterdam UMC, Location AMC, University of Amsterdam, Department of Global Health, and Amsterdam Institute for Global Health and Development, Amsterdam, The Netherlands.
Pythia T NieuwkerkAmsterdam UMC, Location AMC, University of Amsterdam, Department of MedicalPsychology, Amsterdam, The Netherlands.
I Marion Sumari-de BoerKilimanjaro Clinical Research Institute, Moshi, Tanzania, United Republic of.
Amsterdam University Medical Centers · NLKilimanjaro Christian Medical Centre · TZRadboud Institute for Molecular Life Sciences · NLRadboud University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPregnant and breastfeeding Women Living with HIV (WLHIV) often have difficulties in reaching adequate levels of adherence (>95%) to Antiretroviral treatment. "Forgetting" is the most commonly mentioned reason. Sending reminders via SMS is expected to improve adherence. We conducted a pilot study to investigate acceptability, user experience and technical feasibility of sending reminder-SMS to WLHIV.

methodsThis was a 6-months observational pilot-study among WLHIV attending antenatal and postnatal care at Kilimanjaro Christian Medical Centre in Moshi, Tanzania. Women received a reminder-SMS 30 minutes before usual time of intake. One hour later, they received an SMS asking whether they took medication to which they could reply with 'Yes' or 'No'. Messages were sent 3 times a week on randomly chosen days to prevent reliance on daily messages. We calculated the percentage of number of SMS delivered, failed to be delivered, and replied to. We analysed feedback from exit-interviews about experience with the SMS-reminders.

results25 women were enrolled (age 18-45), 2 were lost to follow up. 5,054 messages were sent of which 53 failed to be delivered (1%). 1,880 SMS were sent with a question if medication was taken; 1,012 (54%) messages were replied to, of which 1,003 (99%) were replied with 'YES' and closely to 'YES', and a total of 9 (1%) with 'NO' and 'closely to NO'. 868 messages (46%) were not responded to due to either dropout, change of phone number, loss of phone or network failure. Results from 18 interviews showed that 16 (89%) women were satisfied with SMS reminders. 2 (11%) were concerned about unwanted disclosure because of the content 'don't forget to take medication' and one reported other privacy issues (6%). 3 (17%) women experienced stigma.

conclusion99%of SMS being delivered indicates that SMS reminders in this resource-limited setting are technically feasible. However, concerns regarding privacy were noted, specifically the risk of unwanted disclosure and the experience of stigma. Participants indicated that being made aware of their adherence, motivated them to adhere better. However, personalised and more neutral content of the SMS might be a way to improving the intervention.

Identifiers

PMID34308231
PMCPMC8279205
OpenAlexW3111854238

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.