Evidence map›Paper›PMID 34308182›Full record

ArticleThe East African health research journal2018

Assessing Factors Associated With Survival Among Cervical Cancer Patients in Kenya: A Retrospective Follow-up Study.

Damar Osok, Simon Karanja, Yeri Kombe, Eliud Njuguna, Jim Todd

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Article in The East African health research journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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4citing papers in PubMed
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4 citing papers in PubMed.

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5 · Who and what money

Authors and funding

5 authors.

Damar OsokSchool of Public Health, Jomo Kenyatta University of Agriculture and Technology, Nairobi, Kenya.
Simon KaranjaSchool of Public Health, Jomo Kenyatta University of Agriculture and Technology, Nairobi, Kenya.
Yeri KombeCentre for Public Health Research, Kenya Medical Research Institute, Nairobi, Kenya.
Eliud NjugunaCancer Treatment Centre, Kenyatta National Hospital, Nairobi, Kenya.
Jim ToddDepartment of Population Health, London School of Hygiene and Tropical Medicine, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCervical cancer ranks as the fourth most commonly diagnosed cancer and the fourth leading cause of cancer death in women worldwide. In Kenya, cervical cancer is the second most commonly diagnosed cancer after breast cancer and the leading cause of cancer death in women. It is estimated that by the end of 2018, cervical cancer will be responsible for 5,250 (11%) new cases and 3,286 (11.84%) deaths in Kenya.

methodsWe conducted a retrospective follow-up study to estimate the overall survival of women treated for cervical cancer in Kenya. Medical records were reviewed to extract information for generating a quantitative data set, and the chi-square test was used to test for associations between patient outcomes and various sociodemographic and clinical factors. To estimate overall survival after treatment, we used Kaplan-Meier survival analysis, the logrank test, and Cox proportional hazards regression.

resultsA total of 481 patient records were included in this study. From the bivariate analysis, 4 factors demonstrated a statistically significant association with survival: access to care (

conclusionThe high rate of loss to follow-up appears to be characteristic of cancer care in Kenya and highlights the difficulties in conducting survival studies in low-resource settings with low coverage of vital registration and a lack of centralised national administrative systems. Despite the study's limitations, the results support evidence whereby late-stage diagnosis, deficiencies in cancer management, and limited cancer care services, in particular, have been found to contribute to poor patient outcomes in sub-Saharan Africa.

Identifiers

PMID34308182
PMCPMC8279180

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