Evidence map›Paper›PMID 34308171›Full record

ArticleThe East African health research journal2018

Diagnostic Opportunities for Optimizing Management of Multidrug-Resistant Tuberculosis (MDR-TB) in Tanzania.

Stellah G Mpagama

Open access · diamondAbstract read
In one paragraph

Article in The East African health research journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Stellah G MpagamaKibong'oto Infectious Disease Hospital, Kilimanjaro, Tanzania.
Kilimanjaro Christian Medical Centre · TZ

Funding

Global Infectious Disease Research Training Program AwardD43TW008270 · FIC · UNIVERSITY OF VIRGINIA · PI HOUPT, ERIC R · 2010 to 2014
$735k
FIC NIH HHS D43 TW008270
6 · The paper itself

Abstract

backgroundTanzania is one of the countries confronting a multidrug-resistant tuberculosis (MDR-TB) epidemic. RESEARCH: Research studies on drug susceptibility testing (DST) for second-line TB drugs given to Tanzanian MDR-TB patients has demonstrated mycobacterial resistance to important MDR-TB drugs, such as ethionamide, ofloxacin, amikacin, kanamycin, and pyrazinamide. Likewise, pharmacokinetic studies have shown a high frequency of patients with circulating serum drug levels below the expected ranges, especially for levofloxacin and kanamycin - key drugs in MDR-TB treatment that also affect ex-vivo plasma drug activity. RECOMMENDATIONS: We suggest using molecular diagnostic assays, such as the GenoType MTBDRplus test, and

Identifiers

PMID34308171
PMCPMC8279168
OpenAlexW2998509323

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.