Evidence map›Paper›PMID 34308089›Full record

ArticleJournal of the Endocrine Society2021

CBG Montevideo: A Clinically Novel

Emily Jane Meyer, Lucía Spangenberg, Maria José Ramírez, Sunita Maria Christina De Sousa, Victor Raggio, David James Torpy

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of the Endocrine Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Emily Jane MeyerEndocrine and Metabolic Unit, Royal Adelaide Hospital, Adelaide, SA 5000, Australia.ORCID https://orcid.org/0000-0002-7450-5808
Lucía SpangenbergBioinformatics Unit, Institut Pasteur de Montevideo, Montevideo, 11400, Uruguay.
Maria José RamírezPaediatric Endocrinology, Hospital Británico, Montevideo, 11600, Uruguay.
Sunita Maria Christina De SousaEndocrine and Metabolic Unit, Royal Adelaide Hospital, Adelaide, SA 5000, Australia.
Victor RaggioGenetics Department, Facultad de Medicina, UDELAR, Montevideo, 11800, Uruguay.ORCID https://orcid.org/0000-0001-5389-5002
David James TorpyEndocrine and Metabolic Unit, Royal Adelaide Hospital, Adelaide, SA 5000, Australia.
Royal Adelaide Hospital · AUHospital Británico · UYInstitut Pasteur de Montevideo · UY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Corticosteroid-binding globulin (CBG) is the main transport protein for cortisol, binding up to 90% in a 1:1 ratio. CBG provides transport of cortisol within the circulation and targeted cortisol tissue delivery. Here, we describe the clinically novel "CBG Montevideo" a

Indexed as

corticosteroid binding globulincortisol deficiencyhaploinsufficiencySERPIN A6

Identifiers

PMID34308089
PMCPMC8294686
OpenAlexW3174374162

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.