ArticleKidney international reports2021
Hemodialysis Patients Have Impaired Cerebrovascular Reactivity to CO
Article in Kidney international reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Enhanced external counter pulsation as a novel therapy to maintain cardiac output during hemodialysis: a preliminary randomized controlled study.Scientific reports · 2025Trial
- Quantitative Electroencephalography in Hemodialysis: Scoping Review and Translational Framework.JMIR biomedical engineering · 2026Review
- Intradialytic cerebral blood flow reduction occurs irrespective of vascular access type: a comparative study.BMC nephrology · 2026Article
- Insult to Injury: Dialysis-Induced Cerebrovascular Reactivity and Cognitive Impairment.Kidney360 · 2026Article
- Multiplex functional connectome graph transformer for cognitive vulnerability in dialysis-treated chronic kidney disease.Frontiers in psychiatry · 2026Article
- Dialysis and cognitive impairment.Nature reviews. Nephrology · 2025Review
- Cerebral Haemodynamics and Cognitive Impairment in Chronic Haemodialysis Patients: A Pilot Study.Journal of clinical medicine · 2025Article
- Cerebrovascular Reactivity and Cerebral Ischemia During Chronic Hemodialysis.Hemodialysis international. International Symposium on Home Hemodialysis · 2025Article
- Blunted cerebral hemodynamic responses to incremental exercise in patients with end-stage renal disease.International urology and nephrology · 2024Article
- Hemodynamic and neuromuscular basis of reduced exercise capacity in patients with end-stage renal disease.European journal of applied physiology · 2024Article
- Cerebrovascular carbon dioxide reactivity is intact in chronic kidney disease.Physiological reports · 2024Article
- The Haemodialysis Session Effect on the Choroidal Thickness and Retinal and Choroidal Microcirculation-A Literature Review.Journal of clinical medicine · 2023Review
- Cerebral blood flow pulsatility and cerebral artery stiffness acutely decrease during hemodialysis.Physiological reports · 2023Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionRecurrent hemodialysis (HD)-induced ischemia has emerged as a mechanism responsible for cognitive impairment in HD patients. Impairment of cerebrovascular function in HD patients may render the brain vulnerable to HD-induced ischemic injury. Cerebrovascular reactivity to CO
methodsThis was a single-center prospective observational study carried out at Kidney Clinical Research Unit in London, Canada. We used carefully controlled hypercapnia to interrogate brain vasomotor control. Transcranial Doppler was combined with 10-mm Hg step changes in CO
resultsHD patients had lower CVR than CKD or healthy participants during both intervention and recovery (
conclusionsOur study shows that HD patients have impaired CVR relative to CKD and healthy participants. This renders HD patients vulnerable to ischemic injury during circulatory stress of dialysis and may contribute to the pathogenesis of cognitive impairment.
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