Evidence map›Paper›PMID 34307911›Full record

ArticleClinical and translational radiation oncology2021

Development and results of a patient-reported treatment experience questionnaire on a 1.5 T MR-Linac.

Helen Barnes, Sophie Alexander, Lorna Bower, Jakob Ehlers, Cihan Gani, Trina Herbert, Rebekah Lawes, Pia Krause Møller, Toby Morgan, Marlies E Nowee and 5 more

Registry-linked trialAbstract read
In one paragraph

Article in Clinical and translational radiation oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06965101 (Rapid Response MRI-Guided Palliative Radiotherapy), which is not on this map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06965101 narecruitingnot on this mapstarted 2025, after this paper: background citation

Rapid Response MRI-Guided Palliative Radiotherapy

TypeinterventionalSponsorThe Christie NHS Foundation TrustRan2025 to 2028Enrolled72ConditionsMetastatic Spinal Cord CompressionArmsRadiotherapy to the spine in a single appointment
3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Evaluating participant experiences and tolerability with MR Linac imaging.Technical innovations & patient support in radiation oncology · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Patient expectation and experience of MR-guided radiotherapy using a 1.5T MR-Linac.Technical innovations & patient support in radiation oncology · 2024
    Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Helen BarnesRoyal Marsden NHS Foundation Trust, United Kingdom.
Sophie AlexanderRoyal Marsden NHS Foundation Trust, United Kingdom.
Lorna BowerRoyal Marsden NHS Foundation Trust, United Kingdom.
Jakob EhlersDepartment for Radiation Oncology, University Hospital Tübingen, Tübingen, Germany.
Cihan GaniDepartment for Radiation Oncology, University Hospital Tübingen, Tübingen, Germany.
Trina HerbertRoyal Marsden NHS Foundation Trust, United Kingdom.
Rebekah LawesRoyal Marsden NHS Foundation Trust, United Kingdom.
Pia Krause MøllerOdense University Hospital, Denmark.
Toby MorganRoyal Marsden NHS Foundation Trust, United Kingdom.
Marlies E NoweeNetherlands Cancer Institute, Netherlands.
Gillian SmithRoyal Marsden NHS Foundation Trust, United Kingdom.
Baukelien van TriestNetherlands Cancer Institute, Netherlands.
Neelam TyagiMemorial Sloan Kettering Cancer Centre, United States.
Lee WhitesideThe Christie NHS Foundation Trust, United Kingdom.
Helen McNairRoyal Marsden NHS Foundation Trust, United Kingdom.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Cancer Research UK 28284Department of Health ICA-SCL-2018-04-ST2-002NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

introductionWith the implementation of new radiotherapy technology, it is imperative that patient experience is investigated alongside efficacy and outcomes. This paper presents the development of a specifically designed validated questionnaire and a first report of international multi-institutional preliminary patient experience of MRI-guided adaptive radiotherapy (MRgART) on the 1.5 T MR-Linac (MRL).

methodsA patient experience questionnaire was developed and validated before being distributed to the Elekta MRL Consortium, to gather first patient-reported experience from participating centres worldwide. The final version of the questionnaire contains 18 questions covering a range of themes and was scored on a Likert scale of 0-3. Responses were post-processed so that a score of 0 represents a negative response and 3 represents the most favourable response. These results were analysed for patient-reported experience of treatment on the MRL. Results were also analysed for internal consistency of the questionnaire using Chronbach's Alpha and the questionnaire contents were validated for relevance using content validity indexes (CVI).

results170 responses were received from five centres, representing patients with a wide range of tumour treatment sites from four different countries. MRgART was well tolerated with an 84% favourable response across all questions and respondents. When analysed by theme, all reported the highest percentage of results in the favourable categories (2 and 3). Internal consistency in the questionnaire was high (Cronbach's α = 0.8) and the item-level CVI for each question was 0.78 or above and the Scale-level CVI was 0.93, representing relevant content.

conclusionThe developed questionnaire has been validated as relevant and appropriate for use in reporting experience of patients undergoing treatment on the MRL. The overall patient-reported experience and satisfaction from multiple centres within the Elekta MRL Consortium was consistently high. These results can reinforce user confidence in continuing to expand and develop MRL use in adaptive radiotherapy.

Indexed as

Adaptive RadiotherapyMRI-guidedMR LinacPatient experience

Identifiers

PMID34307911
PMCPMC8283148

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.