Evidence map›Paper›PMID 34307810›Full record

ArticleArthroplasty today2021

Does Preoperative Opioid Consumption Increase the Risk of Chronic Postoperative Opioid Use After Total Joint Arthroplasty?

Samuel T Kunkel, James J Gregory, Matthew J Sabatino, Tracy M Borsinger, Yale A Fillingham, David S Jevsevar, Wayne E Moschetti

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Arthroplasty today, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Persistent Opioid Use Following Major Orthopedic Surgery.Current pain and headache reports · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Samuel T KunkelDepartment of Orthopaedics, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA.
James J GregoryDepartment of Orthopaedics, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA.
Matthew J SabatinoDepartment of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, CT, USA.
Tracy M BorsingerDepartment of Orthopaedics, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA.
Yale A FillinghamDepartment of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA.
David S JevsevarDepartment of Orthopaedics, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA.
Wayne E MoschettiDepartment of Orthopaedics, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA.
Dartmouth–Hitchcock Medical Center · USRush University Medical Center · USYale University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRisk-factor identification related to chronic opioid use after surgery may facilitate interventions mitigating postoperative opioid consumption. We evaluated the relationship between opioid use preceding total hip arthroplasty (THA) and total knee arthroplasty (TKA), and chronic use postoperatively, and the risk of chronic opioid use after total joint arthroplasty.

methodsAll primary THAs and TKAs performed during a 6-month period were identified. Opioid prescription and utilization data (in oxycodone equivalents) were determined via survey and electronic records. Relationship between preoperative opioid use and continued use >90 days after surgery was assessed via Chi-square, with significance set at

resultsA total of 415 patients met inclusion criteria (240 THAs and 175 TKAs). Of the 240 THAs, 199 (82.9%) patients and of the 175 TKAs, 144 (82.3%) patients agreed to participate. Forty-three of 199 (21.6%) THA patients and 22 of 144 (15.3%) TKA patients used opioids within 30 days preoperatively. Nine of 199 (4.5%) THA and 10 of 144 (6.9%) TKA patients had continued use of opioids for >90 days postoperatively. Preoperative opioid consumption was significantly associated with chronic use postoperatively for THA (

conclusionsPreoperative opioid use was associated with nearly 5-fold and 4-fold increase in percentage of patients with chronic opioid use after THA and TKA, respectively. Surgeons should counsel patients regarding this risk and consider strategies to eliminate preoperative opioid use.

Indexed as

ArthroplastyElective surgical proceduresOpioidsOsteoarthritisPain managementPerioperative care

Identifiers

PMID34307810
PMCPMC8283033
OpenAlexW3181338773

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.