Evidence map›Paper›PMID 34307735›Full record

ArticleOpen forum infectious diseases2021

Tuberculous Meningitis: Impact of Timing of Treatment Initiation on Mortality.

Jaime Soria, Alfredo Chiappe, Jorge Gallardo, Joseph R Zunt, Andres G Lescano

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Jaime SoriaDivision of Infectious Diseases, University of Kentucky, Lexington, Kentucky, USA.ORCID https://orcid.org/0000-0002-5863-0502
Alfredo ChiappeDepartment of Infectious Diseases, Hospital Nacional Dos de Mayo, Lima, Peru.
Jorge GallardoDepartment of Infectious Diseases, Hospital Nacional Dos de Mayo, Lima, Peru.
Joseph R ZuntDepartments of Neurology, Global Health, Medicine (Infectious Diseases), and Epidemiology, University of Washington, Seattle, Washington, USA.
Andres G LescanoEmerge, Emerging Diseases and Climate Change Research Unit, School of Public Health and Administration, Universidad Peruana Cayetano Heredia, Lima, Peru.
Pacific Northwest Diabetes Research Institute · USHospital Nacional Dos de Mayo · PEUniversidad Peruana Cayetano Heredia · PEUniversity of Washington · US

Funding

Peru Infectious Diseases Epidemiology Research Training ConsortiumD43TW007393 · FIC · UNIVERSIDAD PERUANA CAYETANO HEREDIA · PI Andres G Lescano · 2005 to 2026
$5.9M
FIC NIH HHS D43 TW007393
6 · The paper itself

Abstract

We conducted a retrospective cross-sectional study of adult hospitalized patients with confirmed tuberculous meningitis to determine the impact of the timing of treatment initiation on mortality. The mortality of tuberculous meningitis patients was high and was associated with delay in initiation of treatment, older age, HIV infection, and higher disease severity at admission.

Indexed as

meningitismortalitytuberculosis

Identifiers

PMID34307735
PMCPMC8297700
OpenAlexW3174933681

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.