Evidence map›Paper›PMID 34307633›Full record

ArticleWorld journal of clinical cases2021

Multidisciplinary team therapy for left giant adrenocortical carcinoma: A case report.

Zheng Zhou, Hong-Mei Luo, Jian Tang, Wu-Jun Xu, Bin-Hui Wang, Xu-Hui Peng, Heng Tan, Li Liu, Xiang-Yang Long, Yu-De Hong and 8 more

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of clinical cases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 1 institution in 1 country.

Zheng ZhouDepartment of Urology, The Second Affiliated Hospital, University of South China, Hengyang 421001, Hunan Province, China.
Hong-Mei LuoDepartment of Histology and Embryology, Clinical Anatomy and Reproductive Medicine Application Institute, University of South China, Hengyang 421001, Hunan Province, China.
Jian TangDepartment of Urology, The Second Affiliated Hospital, University of South China, Hengyang 421001, Hunan Province, China.
Wu-Jun XuDepartment of Urology, The Second Affiliated Hospital, University of South China, Hengyang 421001, Hunan Province, China.
Bin-Hui WangDepartment of Urology, The Second Affiliated Hospital, University of South China, Hengyang 421001, Hunan Province, China.
Xu-Hui PengDepartment of Urology, The Second Affiliated Hospital, University of South China, Hengyang 421001, Hunan Province, China.
Heng TanDepartment of Urology, The Second Affiliated Hospital, University of South China, Hengyang 421001, Hunan Province, China.
Li LiuDepartment of Urology, The Second Affiliated Hospital, University of South China, Hengyang 421001, Hunan Province, China.
Xiang-Yang LongDepartment of Urology, The Second Affiliated Hospital, University of South China, Hengyang 421001, Hunan Province, China.
Yu-De HongDepartment of Urology, The Second Affiliated Hospital, University of South China, Hengyang 421001, Hunan Province, China.
Xiao-Bin WuDepartment of Urology, The Second Affiliated Hospital, University of South China, Hengyang 421001, Hunan Province, China.
Jian-Ping WangDepartment of Endocrinology, The Second Affiliated Hospital of University of South China, Hengyang 421001, Hunan Province, China.
Bai-Qi WangDepartment of Oncology, The Second Affiliated Hospital, University of South China, Hengyang 421001, Hunan Province, China.
Hai-Hui XieDepartment of Radiotherapy , The Second Affiliated Hospital, University of South China, Hengyang 421001, Hunan Province, China.
Yong FangDepartment of Pathology, The Second Affiliated Hospital , University of South China, Hengyang 421001, Hunan Province, China.
Yong LuoDepartment of ICU, The Second Affiliated Hospital, University of South China, Hengyang 421001, Hunan Province, China.
Rong LiDepartment of Clinical Pharmacy, The Second Affiliated Hospital, University of South China, Hengyang 421001, Hunan Province, China.
Yi WangDepartment of Urology, The Second Affiliated Hospital, University of South China, Hengyang 421001, Hunan Province, China. wangwang0906@163.com.
University of South China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdrenocortical carcinoma (ACC) is a rare malignant epithelial tumor originating from adrenocortical cells that carries a very poor prognosis. Metastatic or inoperable diseases are often considered incurable, and treatment remains a challenge. Especially for advanced cases such as ACC complicated with renal venous cancer thrombus, there are few cumulative cases in the literature. CASE SUMMARY: The patient in this case was a 39-year-old middle-aged male who was admitted to the hospital for more than half a month due to dizziness and chest tightness. Computed tomography (CT) findings after admission revealed a left retroperitoneal malignant space-occupying lesion, but the origin of the formation of the left renal vein cancer thrombus remained to be determined. It was speculated that it originated from the left adrenal gland, perhaps a retroperitoneal source, and left adrenal mass + left nephrectomy + left renal vein tumor thrombus removal + angioplasty were performed under general anesthesia. Postoperative pathology results indicated a diagnosis of ACC. Postoperative steroid therapy was administered. At 3 mo after surgery, abdominal CT reexamination revealed multiple enlarged retroperitoneal lymph nodes and multiple low-density shadows in the liver, and palliative radiotherapy and mitotane were administered, considering the possibility of metastasis. The patient is currently being followed up.

conclusionACC is a highly malignant tumor. Even if the tumor is removed surgically, there is still the possibility of recurrence. Postoperative mitotane and adjuvant chemoradiotherapy have certain benefits for patients, but they cannot fully offset the poor prognosis of this disease.

Indexed as

Adrenocortical carcinomaCancer thrombusCase reportKi-67MitotaneMultidisciplinary team

Identifiers

PMID34307633
PMCPMC8281393
OpenAlexW3181908078

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.