Evidence map›Paper›PMID 34307531›Full record

ArticleFrontiers in veterinary science2021

Differential Expression Pattern of Retroviral Envelope Gene in the Equine Placenta.

Valentina Stefanetti, Luisa Pascucci, Sandra Wilsher, Katia Cappelli, Stefano Capomaccio, Lara Reale, Fabrizio Passamonti, Mauro Coletti, Martina Crociati, Maurizio Monaci and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in veterinary science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Valentina StefanettiDepartment of Veterinary Medicine, University of Perugia, Perugia, Italy.
Luisa PascucciDepartment of Veterinary Medicine, University of Perugia, Perugia, Italy.
Sandra WilsherThe Paul Mellon Laboratory of Equine Reproduction, 'Brunswick', Newmarket, United Kingdom.
Katia CappelliDepartment of Veterinary Medicine, University of Perugia, Perugia, Italy.
Stefano CapomaccioDepartment of Veterinary Medicine, University of Perugia, Perugia, Italy.
Lara RealeDepartment of Agricultural, Food and Environmental Sciences, University of Perugia, Perugia, Italy.
Fabrizio PassamontiDepartment of Veterinary Medicine, University of Perugia, Perugia, Italy.
Mauro ColettiDepartment of Veterinary Medicine, University of Perugia, Perugia, Italy.
Martina CrociatiDepartment of Veterinary Medicine, University of Perugia, Perugia, Italy.
Maurizio MonaciDepartment of Veterinary Medicine, University of Perugia, Perugia, Italy.
Maria Luisa MarenzoniDepartment of Veterinary Medicine, University of Perugia, Perugia, Italy.
University of Perugia · ITNewmarket Equine Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endogenous retroviruses (ERVs) are proviral phases of exogenous retroviruses, which have coevolved with vertebrate genomes for millions of years. The conservation of ERV genes throughout evolution suggests their beneficial effects on their hosts' survival. An example of such positive selection is demonstrated by the syncytin gene, which encodes a protein with affinity for various mammalian placentas that is involved in the formation of syncytiotrophoblasts. Although the horse has an epitheliochorial placenta, in which the fetal trophoblasts are simply apposed to the intact uterine epithelium, we have previously demonstrated that the equine ERV (EqERV)

Indexed as

equine endogenous retrovirushorsein situ hybridizationplacentaRT-qPCR

Identifiers

PMID34307531
PMCPMC8298818
OpenAlexW3181751603

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.