Evidence map›Paper›PMID 34307509›Full record

ArticleFrontiers in cardiovascular medicine2021

The β

Simone Pickel, Yiliam Cruz-Garcia, Sandra Bandleon, Katalin Barkovits, Cornelia Heindl, Katharina Völker, Marco Abeßer, Kathy Pfeiffer, Alice Schaaf, Katrin Marcus and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Mapping the interaction surface between CaNature communications · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Simone PickelInstitute of Physiology, University of Würzburg, Würzburg, Germany.
Yiliam Cruz-GarciaInstitute of Physiology, University of Würzburg, Würzburg, Germany.
Sandra BandleonComprehensive Heart Failure Center, University Hospital Würzburg, Würzburg, Germany.
Katalin BarkovitsMedizinisches Proteom-Center, Medical Faculty, Ruhr-University Bochum, Bochum, Germany.
Cornelia HeindlInstitute of Physiology, University of Würzburg, Würzburg, Germany.
Katharina VölkerInstitute of Physiology, University of Würzburg, Würzburg, Germany.
Marco AbeßerInstitute of Physiology, University of Würzburg, Würzburg, Germany.
Kathy PfeifferMedizinisches Proteom-Center, Medical Faculty, Ruhr-University Bochum, Bochum, Germany.
Alice SchaafComprehensive Heart Failure Center, University Hospital Würzburg, Würzburg, Germany.
Katrin MarcusMedizinisches Proteom-Center, Medical Faculty, Ruhr-University Bochum, Bochum, Germany.
Petra Eder-NegrinComprehensive Heart Failure Center, University Hospital Würzburg, Würzburg, Germany.
Michaela KuhnInstitute of Physiology, University of Würzburg, Würzburg, Germany.
Erick Miranda-LaferteInstitute of Physiology, University of Würzburg, Würzburg, Germany.
University of Würzburg · DERuhr University Bochum · DEUniversitätsklinikum Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

L-type voltage-gated calcium channels (LTCCs) regulate crucial physiological processes in the heart. They are composed of the Ca

Indexed as

calpaincalpastatincardiac hypertrophycardiomyocytesCavβ2-subunitL-type voltage-gated calcium channels

Identifiers

PMID34307509
PMCPMC8292724
OpenAlexW3178793267

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.