Evidence map›Paper›PMID 34307500›Full record

ReviewFrontiers in cardiovascular medicine2021

Overview of Veno-Arterial Extracorporeal Membrane Oxygenation (VA-ECMO) Support for the Management of Cardiogenic Shock.

Adamantios Tsangaris, Tamas Alexy, Rajat Kalra, Marinos Kosmopoulos, Andrea Elliott, Jason A Bartos, Demetris Yannopoulos

Abstract readReview
In one paragraph

Review in Frontiers in cardiovascular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Effects of levosimendan on the outcome of veno-arterial extracorporeal membrane oxygenation: a systematic review and meta-analysis.Clinical research in cardiology : official journal of the German Cardiac Society · 2024
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  18. Short-term and mid-term survival of VA-ECMO patients: a single-center experience.Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery · 2025
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4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Adamantios TsangarisDivision of Cardiology, Department of Medicine, University of Minnesota, Minneapolis, MN, United States.
Tamas AlexyDivision of Cardiology, Department of Medicine, University of Minnesota, Minneapolis, MN, United States.
Rajat KalraDivision of Cardiology, Department of Medicine, University of Minnesota, Minneapolis, MN, United States.
Marinos KosmopoulosCenter for Resuscitation Medicine, University of Minnesota School of Medicine, Minneapolis, MN, United States.
Andrea ElliottDivision of Cardiology, Department of Medicine, University of Minnesota, Minneapolis, MN, United States.
Jason A BartosDivision of Cardiology, Department of Medicine, University of Minnesota, Minneapolis, MN, United States.
Demetris YannopoulosDivision of Cardiology, Department of Medicine, University of Minnesota, Minneapolis, MN, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiogenic shock accounts for ~100,000 annual hospital admissions in the United States. Despite improvements in medical management strategies, in-hospital mortality remains unacceptably high. Multiple mechanical circulatory support devices have been developed with the aim to provide hemodynamic support and to improve outcomes in this population. Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is the most advanced temporary life support system that is unique in that it provides immediate and complete hemodynamic support as well as concomitant gas exchange. In this review, we discuss the fundamental concepts and hemodynamic aspects of VA-ECMO support in patients with cardiogenic shock of various etiologies. In addition, we review the common indications, contraindications and complications associated with VA-ECMO use.

Indexed as

cardiogenic shockextracorporeal membrane oxygenationmechanical circulatory supportVA-ECMO complicationsVA-ECMO indications

Identifiers

PMID34307500
PMCPMC8292640

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.