ArticleFrontiers in nutrition2021
Vanillin Activates Human Bitter Taste Receptors TAS2R14, TAS2R20, and TAS2R39.
Article in Frontiers in nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 25 citations in OpenAlex.
- Integrated Metabolomics and Transcriptomics Reveal Bitter Compounds and Synthetic Pathways in the Special-Germplasm Bitter-TastingPlants (Basel, Switzerland) · 2026Article
- Chemosensory tobacco product toxicology part 1: sensory mechanisms.Toxicological sciences : an official journal of the Society of Toxicology · 2025Review
- The Role of Bitter-Tasting Substances in Salivation and Swallowing: Results of the Pilot Study.Foods (Basel, Switzerland) · 2025Article
- Metabolomics analysis reveals the bitter active ingredients inFrontiers in nutrition · 2025Article
- Review
- A comprehensive review of eclectic approaches to the biological synthesis of vanillin and their application towards the food sector.Food science and biotechnology · 2024Review
- Bitter Odorants and Odorous Bitters: Toxicity and Human TAS2R Targets.Journal of agricultural and food chemistry · 2023Article
- Interactions between Beer Compounds and Human Salivary Proteins: Insights toward Astringency and Bitterness Perception.Molecules (Basel, Switzerland) · 2023Article
- Odour hedonics and the ubiquitous appeal of vanilla.Nature food · 2022Review
- The Hidden One: What We Know About Bitter Taste Receptor 39.Frontiers in endocrinology · 2022Review
- Bitter taste sensitivity in domestic dogs (Canis familiaris) and its relevance to bitter deterrents of ingestion.PloS one · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vanilla is widely used in food preparation worldwide for its sensory properties, mainly related to its fragrance, being vanillin the major compound present in the processed vanilla. Vanillin is also known to elicit bitterness as a secondary sensory sensation, but the molecular mechanism of its bitterness has never been reported. Assay buffers of vanillin were tested
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.