Evidence map›Paper›PMID 34307159›Full record

ArticleFrontiers in oncology2021

Identification of Predictive Biomarkers for Lymph Node Involvement in Obese Women With Endometrial Cancer.

Vanessa M López-Ozuna, Liron Kogan, Mahmood Y Hachim, Emad Matanes, Ibrahim Y Hachim, Cristina Mitric, Lauren Liu Chen Kiow, Susie Lau, Shannon Salvador, Amber Yasmeen and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

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  8. Unveiling the oncogenic role of LZTS1 in colorectal cancer.Journal of cellular and molecular medicine · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Vanessa M López-OzunaDivision of Gynecologic Oncology, Jewish General Hospital, McGill University, Montreal, QC, Canada.
Liron KoganDivision of Gynecologic Oncology, Jewish General Hospital, McGill University, Montreal, QC, Canada.
Mahmood Y HachimCollege of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, United Arab Emirates.
Emad MatanesDivision of Gynecologic Oncology, Jewish General Hospital, McGill University, Montreal, QC, Canada.
Ibrahim Y HachimCollege of Medicine, Sharjah Institute for Medical Research, University of Sharjah, Sharjah, United Arab Emirates.
Cristina MitricDivision of Gynecologic Oncology, Jewish General Hospital, McGill University, Montreal, QC, Canada.
Lauren Liu Chen KiowDivision of Gynecologic Oncology, Jewish General Hospital, McGill University, Montreal, QC, Canada.
Susie LauDivision of Gynecologic Oncology, Jewish General Hospital, McGill University, Montreal, QC, Canada.
Shannon SalvadorDivision of Gynecologic Oncology, Jewish General Hospital, McGill University, Montreal, QC, Canada.
Amber YasmeenDivision of Gynecologic Oncology, Jewish General Hospital, McGill University, Montreal, QC, Canada.
Walter H GotliebDivision of Gynecologic Oncology, Jewish General Hospital, McGill University, Montreal, QC, Canada.
Jewish General Hospital · CAMcGill University · CAHadassah Medical Center · ILMohammed Bin Rashid University of Medicine and Health Sciences · AEUniversity of Sharjah · AE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity, an established risk factor for endometrial cancer (EC), is also associated to increased risks of intraoperative and postoperative complications. A reliable tool to identify patients at low risk for lymph node (LN) metastasis may allow minimizing the surgical staging and omit lymphadenectomy in obese patients. To identify molecular biomarkers that could predict LN involvement in obese patients with EC we performed gene expression analysis in 549 EC patients using publicly available transcriptomic datasets. Patients were filtrated according to cancer subtype, weight (>30 kg/m

Indexed as

body mass index (BMI)endometrial cancerlymph nodemolecular markersobesitytumor biomarkers

Identifiers

PMID34307159
PMCPMC8292832
OpenAlexW3178017050

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.