Evidence map›Paper›PMID 34307102›Full record

ArticleWorld journal of plastic surgery2021

Comparative Experimental Study of Dermal Stability: Acellular Dermal Matrix versus Crayopreserved Dermis.

Mahmood Omranifard, Mehdi Rasti Ardakani, Hossein Abdali, Pejman Mortazavi, Saeed Hoseini, Mohammad Ali Hoghoughi

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PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of plastic surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Mahmood OmranifardDepartment of Plastic Surgery, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Mehdi Rasti ArdakaniDepartment of Plastic Surgery, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Hossein AbdaliDepartment of Plastic Surgery, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Pejman MortazaviDepartment of Pathology, School of Specialize Veterinary Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Saeed HoseiniDepartment of Pathology, School of Specialize Veterinary Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Mohammad Ali HoghoughiBurn and Wound Healing Research Center, Shiraz University of Medical Science, Shiraz, Iran.
Isfahan University of Medical Sciences · IRIslamic Azad University, Science and Research Branch · IRShiraz University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGiven the potential usefulness of Acellular Dermal Matrices (ADM) for wound healing, we aimed to evaluate the stability, histological characteristics, and effectiveness of ADM compared with cryopreserved dermis (CPD) in rat models.

methodsThis experimental study was conducted in the Department of Surgery, Isfahan University of Medical Sciences, Isfahan, Iran, from January to March 2015. The prepared ADM and CPD were transplanted to the full-thickness skin defects on the back of Sprague-Dawley rats. Forty-five days after grafting, the tissues were harvested for histological examination. These two types of the dermis' quality and stability were compared with consideration of the following factors; inflammation, fibroblasts migration, vascularization, collagen formation, capsule formation, and microabscess formation.

resultsFrom 19 selected rates, nine received CPD, and ten were treated with ADM. After transplantation, the mean (SD) weight of ADM and CPD grafts were 1.74 (0.07) and 1.45 (0.77), respectively (

conclusionADM have a superior effect than CPD in the wound healing process. Both samples had a similar effect in capsule and microabscesses formation and higher costs of ADM preparation. According to the physicians' decision and evaluation of the process's cost-effectiveness, CPD could be appropriately used as an alternative to ADM.

Indexed as

Acellular dermal matrixCollagenCrayopreserved dermisFibroblastsInflammationPathological neovascularization

Identifiers

PMID34307102
PMCPMC8290440
OpenAlexW3173214415

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.