Evidence map›Paper›PMID 34306903›Full record

ReviewAlcohol research : current reviews2021

Cognitive-Affective Transdiagnostic Factors Associated With Vulnerability to Alcohol and Prescription Opioid Use in the Context of Pain.

Emily L Zale, Jessica M Powers, Joseph W Ditre

Abstract readReview
In one paragraph

Review in Alcohol research : current reviews, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Daily Associations Between Perceived Stress, Pain Intensity, and Alcohol Use Among Veterans With and Without Moderate-to-Severe Chronic Pain.Stress and health : journal of the International Society for the Investigation of Stress · 2026
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Pain catastrophizing, pain anxiety, and substance use among Black individuals with chronic pain who use opioids.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2023
    Article
  14. Review
  15. The hidden risks of alcohol use for pain relief.Alcohol, clinical & experimental research · 2023
    Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Emily L ZaleDepartment of Psychology, Binghamton University, Binghamton, New York.
Jessica M PowersDepartment of Psychology, Syracuse University, Syracuse, New York.
Joseph W DitreDepartment of Psychology, Syracuse University, Syracuse, New York.

Funding

The Alcohol-Pain Connection: Mechanisms and Genetic/Psychological CorrelatesR01AA024844 · NIAAA · SYRACUSE UNIVERSITY · PI DITRE, JOSEPH W., MAISTO, STEPHEN A · 2016 to 2020
$2.0M
Personalized feedback intervention to address hazardous drinking and alcohol-opioid interactions among adults with chronic painR01AA028639 · NIAAA · SYRACUSE UNIVERSITY · PI DITRE, JOSEPH W., ZVOLENSKY, MICHAEL J. · 2020 to 2023
$1.3M
NIAAA NIH HHS R01 AA024844NIAAA NIH HHS R01 AA028639
6 · The paper itself

Abstract

The use of alcohol and prescription opioids is common among people in pain and poses significant public health burdens. This review identifies factors associated with motivation to use alcohol and prescription opioids in the context of pain. Pain-relevant, cognitive-affective, transdiagnostic vulnerability factors-expectancies/motives, pain catastrophizing, pain-related anxiety, distress intolerance, anxiety sensitivity, and perceived interrelations-were selected from theoretical conceptualizations of pain and substance use. Searches conducted in PubMed, PsycINFO, and Embase returned 25 studies that examined associations between identified variables of interest and the use of alcohol and prescription opioids in the context of pain. Consistent with a larger literature on pain and substance use, the studies included in this review demonstrated that people with chronic pain are motivated to use alcohol and opioids in response to negative affect and hold expectancies/motives for coping with pain. Vulnerabilities that engender difficulty managing aversive internal states (distress intolerance and anxiety sensitivity) and maladaptive responses to pain (pain-related anxiety and pain catastrophizing) also were implicated in motivation for alcohol and opioid use. Although one study found that pain-related anxiety was associated with co-use of alcohol and opioids, no studies examined simultaneous use. Future research directions that can explicate causal associations, identify patterns of alcohol and opioid co-use, clarify the role of pain in cessation processes, and inform treatment development are discussed.

Indexed as

Chronic PainOpioid-Related DisordersAnalgesics, OpioidCognitionHumansPrescriptionsAnalgesics, Opioidalcoholalcohol drinkinganalgesicsmotivationopioidspain

Identifiers

PMID34306903
PMCPMC8289456

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.