ArticleACS sustainable chemistry & engineering2021
Wood-Derived Hydrogels as a Platform for Drug-Release Systems.
Article in ACS sustainable chemistry & engineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 167 citations in OpenAlex.
- Valorization of Plant Biomass Through the Synthesis of Lignin-Based Hydrogels for Drug Delivery.Gels (Basel, Switzerland) · 2026Article
- Engineering Lignin-Based Tubular Hydrogel Scaffolds for Load-Bearing Biomedical Applications.ChemSusChem · 2025Article
- Recent Advances in the Use of Ionic Liquids and Deep Eutectic Solvents for Lignocellulosic Biorefineries and Biobased Chemical and Material Production.Chemical reviews · 2025Review
- Study on an Injectable Chitosan-Lignin/Poloxamer Hydrogel Loaded with Platelet-Rich Plasma for Intrauterine Adhesion Treatment.Polymers · 2025Article
- Article
- Biodegradable Natural Hydrogels for Tissue Engineering, Controlled Release, and Soil Remediation.Polymers · 2024Review
- Biomass-Based Antibacterial Hybrid Engineering Hydrogel for Efficient Solar Steam Generation.Chem & bio engineering · 2024Article
- The impact of varying dextran oxidation levels on the inhibitory activity of a bacteriocin loaded injectable hydrogel.Drug delivery and translational research · 2023Article
- Effect of Nanocellulose Types on Microporous Acrylic Acid/Sodium Alginate Super Absorbent Polymers.Journal of functional biomaterials · 2022Article
- Bone tumors effective therapy through functionalized hydrogels: current developments and future expectations.Drug delivery · 2022Review
- Antioxidant, Antimicrobial, and Kinetic Studies of Β-Cyclodextrin Crosslinked with Lignin for Drug Delivery.Pharmaceutics · 2022Article
- Urgent action is required to increase sustainability in in vitro modelling.In vitro models · 2022Article
- Facile Tailoring of Structures for Controlled Release of Paracetamol from Sustainable Lignin Derived Platforms.Molecules (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Wood (cellulose and lignin)-based hydrogels were successfully produced as platforms for drug-release systems. Viscoelastic and cross-linking behaviors of precursor solutions were tuned to produce highly porous hydrogel architectures via freeze-drying. Pore sizes in the range of 100-160 μm were obtained. Varying lignin molecular structure played a key role in tailoring swelling and mechanical performance of these gels with organosolv-type lignin showing optimum properties due to its propensity for intermolecular cross-linking, achieving a compressive modulus around 11 kPa. Paracetamol was selected as a standard drug for release tests and its release rate was improved with the presence of lignin (50% more compared to pure cellulose hydrogels). This was attributed to a reduction in molecular interactions between paracetamol and cellulose. These results highlight the potential for the valorization of lignin as a platform for drug-release systems.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.