Evidence map›Paper›PMID 34306830›Full record

ArticlePeerJ2021

Effect of genetic background on the evolution of Vancomycin-Intermediate

Michelle Su, Michelle H Davis, Jessica Peterson, Claudia Solis-Lemus, Sarah W Satola, Timothy D Read

Open access · goldAbstract read
In one paragraph

Article in PeerJ, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Evolution under vancomycin selection drives divergent collateral sensitivity patterns inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Article
  4. Article
  5. Phenotypic Variation inAntibiotics (Basel, Switzerland) · 2024
    Review
  6. Article
  7. AgrA directly binds to the promoter ofAntimicrobial agents and chemotherapy · 2024
    Article
  8. Average Nucleotide Identity basedbioRxiv : the preprint server for biology · 2024
    Article
  9. Article
  10. Adaptive Laboratory Evolution ofAntibiotics (Basel, Switzerland) · 2023
    Article
  11. Article
  12. Article
  13. Adaptive laboratory evolution and independent component analysis disentangle complex vancomycin adaptation trajectories.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Michelle SuDivision of Infectious Diseases, Department of Medicine, School of Medicine, Emory University, Atlanta, Georgia, USA.ORCID 0000-0002-3212-2120
Michelle H DavisDivision of Infectious Diseases, Department of Medicine, School of Medicine, Emory University, Atlanta, Georgia, USA.
Jessica PetersonDivision of Infectious Diseases, Department of Medicine, School of Medicine, Emory University, Atlanta, Georgia, USA.
Claudia Solis-LemusWisconsin Institute for Discovery and Department of Plant Pathology, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0002-9789-8915
Sarah W SatolaDivision of Infectious Diseases, Department of Medicine, School of Medicine, Emory University, Atlanta, Georgia, USA.
Timothy D ReadDivision of Infectious Diseases, Department of Medicine, School of Medicine, Emory University, Atlanta, Georgia, USA.ORCID 0000-0001-8966-9680
Emory University · USUniversity of Wisconsin–Madison · US

Funding

Antimicrobial Resistance and Therapeutic Discovery Training ProgramT32AI106699 · NIAID · EMORY UNIVERSITY · PI Graeme L Conn, Joanna B Goldberg · 2014 to 2026
$2.7M
Genomics-based prediction of antibiotic failure in S. aureus infectionsR21AI121860 · NIAID · EMORY UNIVERSITY · PI READ, TIMOTHY D., SATOLA, SARAH W · 2016 to 2017
$429k
NIAID NIH HHS R21 AI121860NIAID NIH HHS T32 AI106699
6 · The paper itself

Abstract

Vancomycin-intermediate

Indexed as

EpistasisExperimental evolutionStaphylococcus aureusVancomycin resistance

Identifiers

PMID34306830
PMCPMC8284308
OpenAlexW3182139420

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.