Evidence map›Paper›PMID 34306803›Full record

ArticleACS catalysis2020

Aldehyde Production in Crude Lysate- and Whole Cell-Based Biotransformation Using a Noncanonical Redox Cofactor System.

Kelly N Richardson, William B Black, Han Li

Abstract read
In one paragraph

Article in ACS catalysis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Biological-chemical method for synthesizingSynthetic and systems biotechnology · 2026
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  10. EngineeringACS catalysis · 2024
    Article
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  15. Article
  16. Article
  17. Cell-Free Noncanonical Redox Cofactor Systems.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kelly N RichardsonDepartment of Chemical and Biomolecular Engineering, University of California Irvine, Irvine, California 92697-2700, United States.
William B BlackDepartment of Chemical and Biomolecular Engineering, University of California Irvine, Irvine, California 92697-2700, United States.
Han LiDepartment of Chemical and Biomolecular Engineering, University of California Irvine, Irvine, California 92697-2700, United States.ORCID 0000-0002-6113-6433

Funding

Engineering an unnatural redox cofactor (uRedox) system for efficient biosynthesis of medicinesDP2GM137427 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI LI, HAN · 2019 to 2022
$2.4M
NIGMS NIH HHS DP2 GM137427
6 · The paper itself

Abstract

It is challenging to biosynthesize industrially important aldehydes, which are readily consumed by the numerous alcohol dehydrogenases (ADHs) in cells. In this work, we demonstrate that a nicotinamide mononucleotide (NMN

Indexed as

aldehydebiomimetic cofactorcitronellalEscherichia colinicotinamide mononucleotidenoncanonical redox cofactor

Identifiers

PMID34306803
PMCPMC8294662

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.