Evidence map›Paper›PMID 34306789›Full record

ArticleCase reports in pediatrics2021

COVID-19 Infection in Spinal Muscular Atrophy Associated with Multisystem Inflammatory Syndrome.

Rafat Mosalli, Amirah Al Matrafi, Mohammed A Ghazi, Gamal A Aboumousatafa, Bosco Paes

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Rafat MosalliDepartment of Pediatrics, Umm Al-Qura University, Mecca, Saudi Arabia.ORCID https://orcid.org/0000-0002-4590-2820
Amirah Al MatrafiCollege of Medicine, Umm Al-Qura University, Mecca, Saudi Arabia.ORCID https://orcid.org/0000-0001-7528-5395
Mohammed A GhaziDepartment of Pediatrics, International Extended Care Center, Jeddah, Saudi Arabia.
Gamal A AboumousatafaDepartment of Pediatrics, International Extended Care Center, Jeddah, Saudi Arabia.
Bosco PaesDepartment of Pediatrics (Neonatal Division), McMaster University, Hamilton, ON, Canada.ORCID https://orcid.org/0000-0002-3308-2706
Umm al-Qura University · SAKing Abdulaziz University · SAKing Abdullah International Medical Research Center · SAMcMaster University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The coronavirus disease-2019 (COVID-19) is usually less severe and less prevalent in the pediatric population. Children with preexisting conditions such as neuromuscular impairments and chronic lung disease are more susceptible to COVID-19 and may incur several complications with a poor outcome. We present a case report of a 3-year-old-female with generalized hypotonia and respiratory failure due to spinal muscular atrophy who tested positive for COVID-19 and developed multisystem inflammatory syndrome that was treated with intravenous immunoglobulin and tocilizumab and subsequently died. The report highlights the importance of close surveillance, the use of protective measures during hospital visits, early testing, and diagnosis of COVID-19 in children with neurological disorders.

Identifiers

PMID34306789
PMCPMC8254653
OpenAlexW3175178039

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.