ArticleCase reports in ophthalmological medicine2021
Presumed Retinal Metastasis from Lung Adenocarcinoma: A Case Report and Literature Review.
Article in Case reports in ophthalmological medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 9 citations in OpenAlex.
- Lung Adenocarcinoma With Extensive Vascular Invasion and Retinal Metastasis: A Case Report.Respirology case reports · 2025Article
- Retinal metastasis from lung adenocarcinoma: a case report.Frontiers in oncology · 2025Article
- Insights into Retinal Metastasis from Systemic Carcinoma: A Systematic Review of Clinical and Multimodal Imaging Characteristics.Journal of clinical medicine · 2024Review
- Retinal Metastases as the Initial Presentation of Advanced Lung Adenocarcinoma.European journal of case reports in internal medicine · 2024Article
- Multimodal Imaging, Including Laser Speckle Flowgraphy: A Case of Retinal Metastasis.Cancer diagnosis & prognosisArticle
- Clinical Case Review of Bilateral Retinal Metastasis.Journal of investigative medicine high impact case reportsArticle
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A 63-year-old Caucasian man with metastatic lung adenocarcinoma undergoing chemotherapy and external radiotherapy was referred for routine eye examination. Although he was asymptomatic, ocular examination revealed a relatively well-circumscribed whitish retinal lesion measuring 0.5 × 0.5 × 0.5 mm located along the inferotemporal vascular arcade in the right eye. Optical coherence tomography (OCT) showed a hyperreflective dome-shaped lesion occupying the inner retinal layers with few hyperreflective dots overlying the retina in the posterior vitreous consistent with tumor cells. Fluorescein angiography revealed early hyperfluorescence and late staining without leakage at the lesion site. A diagnosis of presumed retinal metastasis from lung adenocarcinoma was made. At 2 months follow-up after completion of chemotherapy, the retinal lesion was found to have regressed completely leaving minor irregularities in the inner retinal layers on OCT. To date, there have been only 41 cases of carcinoma metastasis to the retina reported in the literature including the current case. Despite its rarity, retinal metastasis should be considered in the differential diagnosis of a white-yellow retinal mass with/without overlying vitreous cells especially in patients with a history of systemic cancer.
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Registered trials
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