Evidence map›Paper›PMID 34306738›Full record

ArticleApplied sciences (Basel, Switzerland)2021

Machine Learning Driven Contouring of High-Frequency Four-Dimensional Cardiac Ultrasound Data.

Frederick W Damen, David T Newton, Guang Lin, Craig J Goergen

Abstract read
In one paragraph

Article in Applied sciences (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Application of 4-D ultrasound-derived regional strain and proteomics analysis inAmerican journal of physiology. Heart and circulatory physiology · 2023
    Article
  4. Localized strain characterization of cardiomyopathy in Duchenne muscular dystrophy using novel 4D kinematic analysis of cine cardiovascular magnetic resonance.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023
    Article
  5. Review
  6. Quantification of murine myocardial infarct size using 2-D and 4-D high-frequency ultrasound.American journal of physiology. Heart and circulatory physiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Frederick W Damen *Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907, USA.ORCID 0000-0001-9213-5508
David T Newton *Department of Statistics, Purdue University, West Lafayette, IN 47907, USA.
Guang LinDepartment of Mathematics & School of Mechanical Engineering, Purdue University, West Lafayette, IN 47907, USA.ORCID 0000-0002-0976-1987
Craig J GoergenWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907, USA.ORCID 0000-0001-8883-7953

Funding

Interdisciplinary Bioengineering Training in Diabetes ResearchT32DK101001 · NIDDK · PURDUE UNIVERSITY · PI EVANS-MOLINA, CARMELLA, VOYTIK-HARBIN, SHERRY L · 2013 to 2022
$1.6M
Spatial Analysis of Cardiac Disease using Murine Four-Dimensional UltrasoundF30HL145980 · NHLBI · PURDUE UNIVERSITY · PI DAMEN, FREDERICK W · 2019 to 2021
$141k
NHLBI NIH HHS F30 HL145980NIDDK NIH HHS T32 DK101001
6 · The paper itself

Abstract

Automatic boundary detection of 4D ultrasound (4DUS) cardiac data is a promising yet challenging application at the intersection of machine learning and medicine. Using recently developed murine 4DUS cardiac imaging data, we demonstrate here a set of three machine learning models that predict left ventricular wall kinematics along both the endo- and epi-cardial boundaries. Each model is fundamentally built on three key features: (1) the projection of raw US data to a lower dimensional subspace, (2) a smoothing spline basis across time, and (3) a strategic parameterization of the left ventricular boundaries. Model 1 is constructed such that boundary predictions are based on individual short-axis images, regardless of their relative position in the ventricle. Model 2 simultaneously incorporates parallel short-axis image data into their predictions. Model 3 builds on the multi-slice approach of model 2, but assists predictions with a single ground-truth position at end-diastole. To assess the performance of each model, Monte Carlo cross validation was used to assess the performance of each model on unseen data. For predicting the radial distance of the endocardium, models 1, 2, and 3 yielded average R

Indexed as

4D ultrasoundboundary predictioncardiac kinematicsechocardiographyhypertrophic cardiomyopathyleft ventriclemachine learningmurinemyocardiumvolumetric imaging

Identifiers

PMID34306738
PMCPMC8301599

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.