Evidence map›Paper›PMID 34306701›Full record

ArticleClinical case reports2021

Lymphangioma of the fetal neck within the PIK3CA-related-overgrowth spectrum (PROS): A case report.

Jann Lennard Scharf, Michael Gembicki, Christoph Dracopoulos, Yorck Hellenbroich, Anne Offermann, Guido Stichtenoth, Kianusch Tafazzoli-Lari, Lars Tharun, Jan Weichert

Open access · goldAbstract readCase Reports
In one paragraph

Article in Clinical case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Alpelisib for the treatment of PIK3CA-related head and neck lymphatic malformations and overgrowth.Genetics in medicine : official journal of the American College of Medical Genetics · 2022
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Jann Lennard ScharfDepartment of Gynecology and Obstetrics University Hospital Schleswig-Holstein, Campus Lübeck Lübeck Germany.ORCID https://orcid.org/0000-0003-3685-6997
Michael GembickiDepartment of Prenatal Medicine and Gynecological Ultrasound University Hospital Schleswig-Holstein, Campus Lübeck Lübeck Germany.
Christoph DracopoulosDepartment of Gynecology and Obstetrics University Hospital Schleswig-Holstein, Campus Lübeck Lübeck Germany.
Yorck HellenbroichInstitute of Human Genetics University Hospital Schleswig-Holstein, Campus Lübeck Lübeck Germany.
Anne OffermannInstitute of Pathology University Hospital Schleswig-Holstein, Campus Lübeck Lübeck Germany.
Guido StichtenothDepartment of Pediatrics University Hospital Schleswig-Holstein, Campus Lübeck Lübeck Germany.
Kianusch Tafazzoli-LariDepartment of Pediatric Surgery University Hospital Schleswig-Holstein, Campus Lübeck Lübeck Germany.
Lars TharunInstitute of Pathology University Hospital Schleswig-Holstein, Campus Lübeck Lübeck Germany.
Jan WeichertDepartment of Prenatal Medicine and Gynecological Ultrasound University Hospital Schleswig-Holstein, Campus Lübeck Lübeck Germany.
University Hospital Schleswig-Holstein · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The delineation of the prenatal diagnostic key features of PIK3CA-related overgrowth spectrum disorders will assume a crucial part in future and a prenatal diagnosis of the causing mutations would provide physicians with a simplified interdisciplinary perinatal management.

Indexed as

cervicalcongenitalfetallymphangiomalymphatic malformationneckPIK3CAPIK3CA‐related‐overgrowth‐spectrumprenatal

Identifiers

PMID34306701
PMCPMC8294145
OpenAlexW3186864453

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.