Evidence map›Paper›PMID 34306696›Full record

ArticleClinical case reports2021

Prenatal cases with rare RIT1 variants causing severe fetal hydrops and death.

Ieva Miceikaite, Geske Sidsel Bak, Martin Jakob Larsen, Britta Schlott Kristiansen, Pernille Mathiesen Torring

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ieva MiceikaiteDepartment of Clinical Genetics Odense University Hospital Odense Denmark.ORCID https://orcid.org/0000-0002-5188-7647
Geske Sidsel BakFetal Medicine Unit Department of Obstetrics and Gynecology Odense University Hospital Odense Denmark.
Martin Jakob LarsenDepartment of Clinical Genetics Odense University Hospital Odense Denmark.
Britta Schlott KristiansenDepartment of Clinical Genetics Odense University Hospital Odense Denmark.
Pernille Mathiesen TorringDepartment of Clinical Genetics Odense University Hospital Odense Denmark.ORCID https://orcid.org/0000-0002-7303-7619
Odense University Hospital · DKUniversity of Southern Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe two clinical prenatal cases with rare de novo RIT1 variants, which showed more severe clinical manifestations than other Noonan Syndrome genotypes, resulting in fetal death. Extra attention is recommended when these variants are detected.

Indexed as

cystic hygromahydrops fetalisNoonan syndromeprenatal screeningRIT1

Identifiers

PMID34306696
PMCPMC8294143
OpenAlexW3183851763

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.