ReviewJournal of dental sciences2021
Review of oral ulcerative lesions in COVID-19 patients: A comprehensive study of 51 cases.
Review in Journal of dental sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Oral mucosa lesions in confirmed and non-vaccinated cases for COVID-19: A systematic review.Journal of stomatology, oral and maxillofacial surgery · 2022Pooled it
- SARS-CoV-2 nonspike structural proteins hijack mucosa epithelial cell fate.Cell death & disease · 2026Article
- Neural network models for diagnosing recurrent aphthous ulcerations from clinical oral images.Scientific reports · 2025Article
- COVID-19 Influence on Mandibular Dry Socket Occurrence.World journal of plastic surgery · 2025Article
- Evaluation of oral health status and immunological parameters of hospitalized COVID-19 patients during acute and recovery phases: A randomized clinical trial.Journal of dental sciences · 2024Article
- Awareness of undergraduate dental students, interns, and freshly graduated dentists about oral manifestation associated with COVID-19.BMC oral health · 2023Article
- Risk indicators for oral ulcers among people living with HIV during the first wave of the pandemic: a cross sectional study.BMC oral health · 2023Article
- Central nervous system reactivation of herpesviridae family in patients with COVID-19.Journal of neurovirology · 2023Article
- Oral lesions in patients with severe COVID-19 in the National Institute of Respiratory Diseases in Mexico: Case series.Journal of dental research, dental clinics, dental prospects · 2023Article
- Oral aphthous ulcers associated with COVID-19.Visual journal of emergency medicine · 2022Article
- Associations between Emotional Distress, Sleep Changes, Decreased Tooth Brushing Frequency, Self-Reported Oral Ulcers and SARS-Cov-2 Infection during the First Wave of the COVID-19 Pandemic: A Global Survey.International journal of environmental research and public health · 2022Article
- Oral Lesions Associated with COVID-19 and the Participation of the Buccal Cavity as a Key Player for Establishment of Immunity against SARS-CoV-2.International journal of environmental research and public health · 2022Review
- Lack of direct association between oral mucosal lesions and SARS-CoV- 2 in a cohort of patients hospitalised with COVID-19.Journal of oral microbiology · 2022Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Numerous oral manifestations of COVID-19 have been reported in the literatures. Common oral lesions in COVID-19 patients included ulcerations, xerostomia, dysgeusia, gingival inflammation, and erythema. Among them, oral ulceration is the most frequent finding and is present as various but distinct patterns. Thus, we conducted a comprehensive review of 51 COVID-19 patients with oral ulcerative lesions to further analyze the various oral ulcerative lesions in COVID-19 patients. There were a median age of 41.4 years and a slight female predilection in these patients. Most oral lesions manifested as an aphtha-like ulceration but lack of an evidence of recurrent aphthous stomatitis. Some of them were present as herpetiform ulcerations without HSV infection. Widespread ulcerations accompanied with necrosis were observed in the more severe and immunosuppressed older patients. Although some reported patients were asymptomatic, most of them had systemic symptoms concurring or slightly preceding the oral ulcerative lesions and the latency from the onset of systemic symptoms to oral ulcerative lesions were under 10 days, suggesting that oral ulceration was one of the early symptoms of COVID-19. Therefore, the oral ulcerative lesions may be considered as oral markers for early diagnosis of the underlying COVID-19 infection in the asymptomatic patients.
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Registered trials
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