Evidence map›Paper›PMID 34306452›Full record

ArticleAmerican journal of translational research2021

Diagnostic significance of transcranial doppler combined with carotid ultrasound in patients with cerebral ischemic stroke.

Huijun Wang, Li Fei, Hongbo Xia, Qian Zhang, Youping Huang

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05706168 (A Study to Investigate the Effects of Aerobic Exercise Training), which is not on this map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05706168 naunknown statusnot on this mapstarted 2023, after this paper: background citation

A Study to Investigate the Effects of Aerobic Exercise Training (AET) on the Large Intracranial and Extracranial Cerebral Arteries and the Cognitive and Motor Functions in Post Stroke Patients.

TypeinterventionalSponsorThe Hong Kong Polytechnic UniversityRan2023 to 2024Enrolled120ConditionsStrokeArmstreadmill exercise, Cycle ergometer exercise
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Huijun WangDepartment of Ultrasound, Jingzhou Second People's Hospital Jingzhou, Hubei Province, China.
Li FeiDepartment of Ultrasound, Jingzhou Second People's Hospital Jingzhou, Hubei Province, China.
Hongbo XiaDepartment of Ultrasound, Jingzhou Second People's Hospital Jingzhou, Hubei Province, China.
Qian ZhangDepartment of Ultrasound, Jingzhou Second People's Hospital Jingzhou, Hubei Province, China.
Youping HuangDepartment of Ultrasound, Jingzhou Second People's Hospital Jingzhou, Hubei Province, China.
Jingzhou Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the diagnostic value of transcranial doppler (TCD) combined with carotid ultrasound (CU) in cerebral ischemic stroke (CIS).

methodsA total of 68 patients with CIS who were treated in our hospital from September 2018 to September 2020 were selected as the research group, and another 68 patients with non-CIS admitted during the same period were selected as the reference group. Both groups underwent TCD and CU examinations to compare their diagnostic values.

resultsThere were no distinct differences concerning clinical data such as gender ratio, age, BMI value, smoking history, residence, and complications between the two groups (P > 0.05). The carotid artery intima-media thickening was reported at a markedly higher rate in the research group compared to the reference group (P < 0.001). It was indicated by the CU examination that the degree of carotid artery stenosis in the research group was more severe compared with the reference group (P < 0.05). The patients in the research group experienced more severe intracranial artery stenosis relative to the reference group by the TCD examination (P < 0.05). The plaque morphology of the research group was predominantly irregular, and the internal echoes were predominantly hypoechoic. The plaque morphology in the reference group was predominantly regular, and the internal echoes were predominantly isoechoic. There was remarkably higher incidence of the research group (78%) with ulcer as compared to the reference group (P < 0.05), and no marked difference was observed in the incidence of calcification (P > 0.05). The combined diagnostic approach was superior to TCD and CUS alone in the terms of accuracy, sensitivity and specificity (P < 0.001).

conclusionTCD combined with CU can greatly improve the diagnostic efficiency of CIS, and provide more evidence for clinical therapy. It deserves promotion and use.

Indexed as

carotid ultrasoundcerebral ischemic strokediagnostic significanceTranscranial doppler ultrasound

Identifiers

PMID34306452
PMCPMC8290762
OpenAlexW3186952161

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.