ArticleAmerican journal of translational research2021
The effects of early enteral nutrition on the nutritional statuses, gastrointestinal functions, and inflammatory responses of gastrointestinal tumor patients.
Article in American journal of translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- Efficacy and safety of nutrition therapy for patients undergoing abdominal surgery: a systematic review and network meta-analysis.European journal of clinical nutrition · 2025Pooled it
- Effects of food and gastrointestinal secretions on intestinal integrity in an experimental rat model.Experimental and therapeutic medicine · 2026Article
- Immunomodulatory Effects of L-Arginine-Modified Silkworm Pupae Protein Enteral Nutrition on Murine Intestinal Morphology and Immunity.International journal of molecular sciences · 2025Article
- Serum PM20D1 levels are associated with nutritional status and inflammatory factors in gastric cancer patients undergoing early enteral nutrition.Open medicine (Warsaw, Poland) · 2025Article
- Efficacy of early enteral nutrition support on the nutritional status of patients after gallstone surgery.PloS one · 2025Article
- Application of early enteral nutrition nursing based on enhanced recovery after surgery theory in patients with digestive surgery.World journal of gastrointestinal surgery · 2023Article
- Article
- Clinical Benefits of Routine Feeding Jejunostomy Tube Placement in Patients Undergoing Esophagectomy.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2022Article
- The Effect of Different Nutritional Nursing Support on the Nutritional Status and Disease Recovery of Elderly Patients with Gastrointestinal Tumors during the Perioperative Period.Computational and mathematical methods in medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis paper was designed to investigate the effects of early enteral nutrition (EEN) on the nutritional statuses, gastrointestinal functions, and inflammatory responses of gastrointestinal tumor patients.
methodsA total of 194 gastrointestinal tumor patients treated in our hospital from May 2017 to February 2019 were recruited as the study cohort. Among them, 101 patients were administered enteral nutrition (the study group), and 93 patients were administered parenteral nutrition (the control group). The two groups were compared in terms of their nutritional statuses, gastrointestinal functions, inflammatory responses, and other indicators.
resultsOn the third day after the operation (postoperative 3 d), the serum albumin (ALB) and prealbumin (PA) levels were significantly reduced in both groups (P>0.05). On the seventh day after the operation (postoperative 7 d), the two nutritional indices increased significantly in both groups (P<0.05), and were significantly higher in the study group (P<0.05). Compared with the control group, the patients in the study group experienced shorter lengths of stay (LOS), earlier first anal exhaust times, and faster intestinal peristalsis recovery times (P<0.05). On the third day after the operations, the high-sensitive C-reactive protein (hs-CRP) and prostaglandin E (PGE) levels were significantly reduced in both groups (P<0.05), and the decrease was significantly greater in the study group (P<0.05). In addition, the CD3
conclusionFor gastrointestinal tumor patients, EEN can improve their gastrointestinal functions, enhance their immune functions, and reduce their expressions of inflammatory cytokines while improving their nutritional statuses and QOL.
Indexed as
Identifiers
34306365PMC8290805W3186614353What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.