Evidence map›Paper›PMID 34306358›Full record

ArticleAmerican journal of translational research2021

Factors affecting recurrent positive RT-PCR results in clinically cured COVID-19 patients: a multicenter study.

You Zou, Jia-Ni Zou, Ya-Se Zhuang, Bin-Ru Wang, Liu Sun, Shan Xu, Sheng-Lan Li, Li-Jun Shen, Geng-Tian Liang, Qing-Quan Hua and 2 more

Abstract read
In one paragraph

Article in American journal of translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Machine Learning Approach for Autonomous Detection and Classification of COVID-19 Virus.Computers & electrical engineering : an international journal · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

You ZouDepartment of Otolaryngology-Head and Neck Surgery, Renmin Hospital of Wuhan University Wuhan 430060, Hubei, P. R. China.
Jia-Ni ZouDepartment of Radiology, General Hospital of The Central Theater Command of The People's Liberation Army Wuhan 430070, Hubei, P. R. China.
Ya-Se ZhuangDepartment of Critical Care Medicine, Taihe Hospital (Affiliated Hospital of Hubei University of Medicine) Shiyan 442000, Hubei, P. R. China.
Bin-Ru WangDepartment of Otolaryngology-Head and Neck Surgery, Tongren Hospital of Wuhan University (Wuhan Third Hospital) Wuhan 430060, Hubei, P. R. China.
Liu SunDepartment of Otolaryngology-Head and Neck Surgery, General Hospital of The Central Theater Command of The People's Liberation Army Wuhan 430070, Hubei, P. R. China.
Shan XuDepartment of Otolaryngology-Head and Neck Surgery, Renmin Hospital of Wuhan University Wuhan 430060, Hubei, P. R. China.
Sheng-Lan LiDepartment of Radiology, Renmin Hospital of Wuhan University Wuhan 430060, Hubei, P. R. China.
Li-Jun ShenDepartment of Otolaryngology-Head and Neck Surgery, Renmin Hospital of Wuhan University Wuhan 430060, Hubei, P. R. China.
Geng-Tian LiangDepartment of Otolaryngology-Head and Neck Surgery, Tongren Hospital of Wuhan University (Wuhan Third Hospital) Wuhan 430060, Hubei, P. R. China.
Qing-Quan HuaDepartment of Otolaryngology-Head and Neck Surgery, Renmin Hospital of Wuhan University Wuhan 430060, Hubei, P. R. China.
Wen-Cai HuangDepartment of Radiology, General Hospital of The Central Theater Command of The People's Liberation Army Wuhan 430070, Hubei, P. R. China.
Shi-Ming ChenDepartment of Otolaryngology-Head and Neck Surgery, Renmin Hospital of Wuhan University Wuhan 430060, Hubei, P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to evaluate factors affecting the recurrence of positive RT-PCR results. By performing a retrospective analysis, we evaluated the clinical data of recurrent positive coronavirus disease 2019 (COVID-19) patients in multiple medical institutions in Wuhan. We recruited COVID-19 patients who were hospitalized from January 1 to March 10, 2020, in three tertiary hospitals in Wuhan, met the discharge criteria and received at least one additional nucleic acid test before leaving the hospital. According to the RT-PCR results, patients were split into a recurrent positive group (RPos group) and a nonrecurrent positive group (non-RPos group). Clinical characteristics, therapeutic schedules and antibody titers were compared between the two groups. AI-assisted chest high-resolution computed tomography (HRCT) technology was applied to investigate pulmonary inflammatory exudation and compare the extent of lung areas with different densities. This study involved 122 COVID-19 patients. There were no significant differences in age, sex, preexisting diseases, clinical symptoms, clinical classification, course of disease, therapeutic schedules or serum-specific antibodies between the two groups. A higher proportion of patients who showed pulmonary inflammatory exudation on HRCT scans were recurrent positive at the time of discharge than other patients (81.6% vs 13.7%,

Indexed as

AI-assistedCOVID-19CTrecurrent positive

Identifiers

PMID34306358
PMCPMC8290760

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.