ArticleInternational journal of endocrinology2021
Association between Lipid Profiles and Serum Urate: A Cross-Sectional Study in Southwestern China.
Article in International journal of endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
7 citing papers in PubMed, 12 citations in OpenAlex.
- Cross-sectional analysis of triglycerides and serum uric acid association in ovarian cancer patients.Frontiers in oncology · 2025Article
- Fatty acid oxidation-induced HIF-1α activation facilitates hepatic urate synthesis through upregulating NT5C2 and XDH.Life metabolism · 2024Article
- Associations between lipid-lowering drugs and urate and gout outcomes: a Mendelian randomization study.Frontiers in endocrinology · 2024Article
- Insulin use and gout risk among patients with type 2 diabetes mellitus: a real-world cohort study in Shanghai, China.Clinical rheumatology · 2023Article
- Sex-related differences in the hypertriglyceridemic-waist phenotype in association with hyperuricemia: a longitudinal cohort study.Lipids in health and disease · 2023Article
- Association between Gout and Dyslipidemia: A Nested Case-Control Study Using a National Health Screening Cohort.Journal of personalized medicine · 2022Article
- Risk factors and management of hyperuricemia after renal transplantation.Frontiers in surgery · 2022Review
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe relationship between lipid profiles and serum urate has not been fully investigated. This study aims to investigate the sex- and age-specific association between lipid profiles and serum urate.
methodsThis was a cross-sectional study involving 122,351 participants aged 18-99 years from a check-up centre in Southwestern China. Generalized additive models and smooth curve fitting were conducted to explore the association between components of lipid profiles and serum urate. Furthermore, multivariate linear and logistic regression models were also performed.
resultsIn generalized additive models, the fitted smoothing curves showed that serum urate fluctuated in a small range with total cholesterol, LDL-C, or HDL-C raising. After adjusting for confounders, the differences in serum urate progressively increased with raising serum triglycerides quartiles. The likelihood (odds ratio, OR) for developing serum urate > 420
conclusionsSerum urate and the likelihood for developing serum urate >420
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.