Evidence map›Paper›PMID 34305885›Full record

ArticleFrontiers in immunology2021

PTX3 Deficiency Promotes Enhanced Accumulation and Function of CD11c

Jyoti Balhara, Latifa Koussih, Ashfaque Mohammed, Lianyu Shan, Bouchaib Lamkhioued, Abdelilah S Gounni

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Jyoti BalharaDepartment of Immunology, Max-Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada.
Latifa KoussihDepartment of Immunology, Max-Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada.
Ashfaque MohammedDepartment of Immunology, Max-Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada.
Lianyu ShanDepartment of Immunology, Max-Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada.
Bouchaib LamkhiouedLaboratoire d'Immunologie et de Biotechnologies, EA7509-IRMAIC, Pôle-Santé, Université de Reims Champagne-Ardenne, Reims, France.
Abdelilah S GounniDepartment of Immunology, Max-Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada.
University of Manitoba · CAImmuno-Régulation des Maladies Auto- immunes Inflammatoires et Cancer · FR

Funding

CIHR
6 · The paper itself

Abstract

PTX3 is a unique member of the long pentraxins family and plays an indispensable role in regulating the immune system. We previously showed that PTX3 deletion aggravates allergic inflammation

Indexed as

AllergensAnimalsCD11b AntigenCD11c AntigenC-Reactive ProteinDendritic CellsDisease Models, AnimalFemaleMiceMice, KnockoutNerve Tissue ProteinsOvalbuminPentraxinsRespiratory HypersensitivityAllergensCD11b AntigenCD11c AntigenC-Reactive ProteinNerve Tissue ProteinsOvalbuminPentraxinsallergen uptakeallergic inflammationasthmachemokinesdendritc cellsmonocytesPTX3 protein

Identifiers

PMID34305885
PMCPMC8299994
OpenAlexW3178072697

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.