Evidence map›Paper›PMID 34305778›Full record

ArticleFrontiers in neurology2021

Recurrent Lobar Hemorrhages and Multiple Cortical Superficial Siderosis in a Patient of Alzheimer's Disease With Homozygous APOE ε2 Allele Presenting Hypobetalipoproteinemia and Pathological Findings of

Masaki Ikeda, Koichi Okamoto, Keiji Suzuki, Eriko Takai, Hiroo Kasahara, Natsumi Furuta, Minori Furuta, Yuichi Tashiro, Chisato Shimizu, Shin Takatama and 13 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. eNeurologicalSci · 2025
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 4 institutions in 1 country.

Masaki IkedaDivision of General Education (Neurology), Faculty of Health & Medical Care, Saitama Medical University, Saitama, Japan.
Koichi OkamotoDepartment of Neurology, Geriatrics Research Institute and Hospital, Maebashi, Japan.
Keiji SuzukiDepartment of Pathology, Geriatrics Research Institute and Hospital, Maebashi, Japan.
Eriko TakaiDepartment of Neurology, Gunma University Graduate School of Medicine, Maebashi, Japan.
Hiroo KasaharaDepartment of Neurology, Gunma University Graduate School of Medicine, Maebashi, Japan.
Natsumi FurutaDepartment of Neurology, Gunma University Graduate School of Medicine, Maebashi, Japan.
Minori FurutaDepartment of Neurology, Gunma University Graduate School of Medicine, Maebashi, Japan.
Yuichi TashiroDepartment of Neurology, Mito Medical Center, Mito, Japan.
Chisato ShimizuDepartment of Neurology, Geriatrics Research Institute and Hospital, Maebashi, Japan.
Shin TakatamaDepartment of Neurosurgery, Geriatrics Research Institute and Hospital, Maebashi, Japan.
Isao NaitoDepartment of Neurosurgery, Geriatrics Research Institute and Hospital, Maebashi, Japan.
Mie SatoDepartment of Anesthesiology, Geriatrics Research Institute and Hospital, Maebashi, Japan.
Yasujiro SakaiDepartment of Neurology, Geriatrics Research Institute and Hospital, Maebashi, Japan.
Manabu TakahashiDepartment of Cardiovascular Medicine, Gunma University Graduate School of Medicine, Maebashi, Japan.
Masakuni AmariDepartment of Neurology, Geriatrics Research Institute and Hospital, Maebashi, Japan.
Masamitsu TakatamaDepartment of Neurology, Geriatrics Research Institute and Hospital, Maebashi, Japan.
Tetsuya HiguchiDepartment of Diagnostic Radiology and Nuclear Medicine, Gunma University Graduate School of Medicine, Maebashi, Japan.
Yoshito TsushimaDepartment of Diagnostic Radiology and Nuclear Medicine, Gunma University Graduate School of Medicine, Maebashi, Japan.
Hideaki YokooDivision of Endocrinology and Metabolism, Department of Internal Medicine, Jichi Medical University, Tochigi, Japan.
Masahiko KurabayashiDepartment of Pathology, Gunma University Graduate School of Medicine, Maebashi, Japan.
Shun IshibashiDivision of Endocrinology and Metabolism, Department of Internal Medicine, Jichi Medical University, Tochigi, Japan.
Kenji IshiiTeam for Neuroimaging, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan.
Yoshio IkedaDepartment of Neurology, Gunma University Graduate School of Medicine, Maebashi, Japan.
Gunma University · JPJichi Medical University · JPNational Hospital Organization Mito Medical Center · JPTokyo Metropolitan Institute of Gerontology · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In Alzheimer's disease, the apolipoprotein E gene

Indexed as

11C-PiB PET18F-THK5351 PETAlzheimer's diseaseapolipoprotein ϵ allelecerebral amyloid angiopathycortical superficial siderosishypobetalipoproteinemiarecurrent lobar brain hemorrhages

Identifiers

PMID34305778
PMCPMC8294698
OpenAlexW3180596077

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.