Evidence map›Paper›PMID 34305539›Full record

ArticleFrontiers in neuroanatomy2021

Lack of the Transient Receptor Potential Vanilloid 1 Shifts Cannabinoid-Dependent Excitatory Synaptic Plasticity in the Dentate Gyrus of the Mouse Brain Hippocampus.

Jon Egaña-Huguet, Miquel Saumell-Esnaola, Svein Achicallende, Edgar Soria-Gomez, Itziar Bonilla-Del Río, Gontzal García Del Caño, Sergio Barrondo, Joan Sallés, Inmaculada Gerrikagoitia, Nagore Puente and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroanatomy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
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  4. CaInternational journal of molecular sciences · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Jon Egaña-HuguetDepartment of Neurosciences, Faculty of Medicine and Nursing, University of the Basque Country UPV/EHU, Leioa, Spain.
Miquel Saumell-EsnaolaDepartment of Pharmacology, Faculty of Pharmacy, Centro de Investigación Biomédica en Red de Salud Mental, University of the Basque Country UPV/EHU, Vitoria-Gasteiz, Spain.
Svein AchicallendeDepartment of Neurosciences, Faculty of Medicine and Nursing, University of the Basque Country UPV/EHU, Leioa, Spain.
Edgar Soria-GomezDepartment of Neurosciences, Faculty of Medicine and Nursing, University of the Basque Country UPV/EHU, Leioa, Spain.
Itziar Bonilla-Del RíoDepartment of Neurosciences, Faculty of Medicine and Nursing, University of the Basque Country UPV/EHU, Leioa, Spain.
Gontzal García Del CañoBioaraba, Neurofarmacología Celular y Molecular, Vitoria-Gasteiz, Spain.
Sergio BarrondoDepartment of Pharmacology, Faculty of Pharmacy, Centro de Investigación Biomédica en Red de Salud Mental, University of the Basque Country UPV/EHU, Vitoria-Gasteiz, Spain.
Joan SallésDepartment of Pharmacology, Faculty of Pharmacy, Centro de Investigación Biomédica en Red de Salud Mental, University of the Basque Country UPV/EHU, Vitoria-Gasteiz, Spain.
Inmaculada GerrikagoitiaDepartment of Neurosciences, Faculty of Medicine and Nursing, University of the Basque Country UPV/EHU, Leioa, Spain.
Nagore PuenteDepartment of Neurosciences, Faculty of Medicine and Nursing, University of the Basque Country UPV/EHU, Leioa, Spain.
Izaskun ElezgaraiDepartment of Neurosciences, Faculty of Medicine and Nursing, University of the Basque Country UPV/EHU, Leioa, Spain.
Pedro GrandesDepartment of Neurosciences, Faculty of Medicine and Nursing, University of the Basque Country UPV/EHU, Leioa, Spain.
University of the Basque Country · ESAchucarro Basque Center for Neuroscience · ESCentro de Investigación Biomédica en Red de Salud Mental · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The transient receptor potential vanilloid 1 (TRPV1) participates in synaptic functions in the brain. In the dentate gyrus, post-synaptic TRPV1 in the granule cell (GC) dendritic spines mediates a type of long-term depression (LTD) of the excitatory medial perforant path (MPP) synapses independent of pre-synaptic cannabinoid CB

Indexed as

CB1 receptorendovanilloid systemexcitatory synapsesG proteinslong-term potentiation

Identifiers

PMID34305539
PMCPMC8294191
OpenAlexW3180385194

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.