ArticleFrontiers in neuroscience2021
Altered Gray Matter Volume and Functional Connectivity in Patients With Vestibular Migraine.
Article in Frontiers in neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 4 of them syntheses that pooled it.
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Who cites it
27 citing papers in PubMed, 4 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- The cerebellum in migraine: a narrative review of anatomical, imaging, and clinical evidence.Frontiers in neurology · 2026Pooled it
- Coordinates-based meta-analysis for vestibular migraine and the underlying mechanisms behind it.Frontiers in neurology · 2025Pooled it
- The altered functional status in vestibular migraine: A meta-analysis.Brain and behavior · 2024Pooled it
- Brain functional connectivity in hyperthyroid patients: systematic review.Frontiers in neuroscience · 2024Pooled it
- Exploring the complex relationship between vestibular symptoms and migraine: a resting‑state functional MRI study.Brain imaging and behavior · 2026Article
- Vestibular cortex-related effective connectivity signatures: characterization and differentiation of vestibular migraine patients via magnetic resonance imaging and machine learning.The journal of headache and pain · 2026Article
- Glutamatergic pathway from deep layers of the insular cortex to the rostral central medial thalamic nucleus participates in neuropathic pain and anxiety-like behaviors in mice.The journal of headache and pain · 2026Article
- Associations between pain experiences and gray matter volume in youth in the adolescent brain cognitive development (ABCD) study.The journal of pain · 2025Article
- Functional and Structural Differences of Brain in Patients With Vestibular Migraine: A Resting-State Functional MRI and DTI Study.Brain and behavior · 2025Article
- Abnormal Functional Network Centrality and Causal Connectivity in Migraine Without Aura: A Resting-State fMRI Study.Brain and behavior · 2025Article
- Potential neural mechanisms of acupuncture therapy on migraine: a systematic review and activation likelihood estimation meta-analysis update.Quantitative imaging in medicine and surgery · 2025Article
- Disrupted gray matter connectome in vestibular migraine: a combined machine learning and individual-level morphological brain network analysis.The journal of headache and pain · 2024Article
- Aberrant cerebral blood flow and functional connectivity in patients with vestibular migraine: a resting-state ASL and fMRI study.The journal of headache and pain · 2024Article
- Vestibular Migraine Pathophysiology and Treatment: a Narrative Review.Current pain and headache reports · 2024Review
- Altered parietal operculum cortex 2 functional connectivity in benign paroxysmal positional vertigo patients with residual dizziness: A resting-state fMRI study.CNS neuroscience & therapeutics · 2024Article
- Localization of Vestibular Cortex Using Electrical Cortical Stimulation: A Systematic Literature Review.Brain sciences · 2024Review
- Neurocognitive Adaptations for Spatial Orientation and Navigation in Astronauts.Brain sciences · 2023Article
- Vestibular and Oculomotor Findings in Vestibular Migraine Patients.Audiology research · 2023Article
- Altered functional brain network patterns in patients with migraine without aura after transcutaneous auricular vagus nerve stimulation.Scientific reports · 2023Article
- Aberrant dynamic functional network connectivity in vestibular migraine patients without peripheral vestibular lesion.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
subjectsVestibular migraine (VM) is the most common neurological cause of vertigo in adults. Previous neuroimaging studies have reported structural alterations in areas associated with pain and vestibular processing. However, it is unclear whether altered resting-state functional connectivity (FC) exists in brain regions with structural abnormalities in patients with VM.
methodsResting-state functional magnetic resonance imaging (MRI) and three-dimensional T1-weighed MRI were performed in 30 patients with VM and 30 healthy controls (HCs). Patients underwent an evaluation of migraine and dizziness severity. FC and voxel-based morphometry (VBM) were performed using DPABI 4.3 and CAT12, respectively. The association between changes in gray matter (GM) volume or FC and clinical parameters was also analyzed.
resultsCompared with HCs, patients with VM demonstrated a reduced GM volume in the bilateral parietoinsular vestibular cortex (PIVC), right middle frontal gyrus, and precuneus. The GM volume of the left PIVC was negatively associated with Dizziness Handicap Inventory score in patients with VM. Taking this region as a seed region, we further observed increased FC between the left primary somatosensory cortex (S1)/inferior parietal lobule (IPL) and the left PIVC in patients with VM.
conclusionFC between regions with a decline in GM volume (the PIVC and S1/IPL) is altered in patients with VM, suggesting that abnormalities in vestibular cortical network could be useful for understanding the underlying mechanisms of VM.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.