Evidence map›Paper›PMID 34305304›Full record

ArticleStatistical science : a review journal of the Institute of Mathematical Statistics2021

Network Modeling in Biology: Statistical Methods for Gene and Brain Networks.

Y X Rachel Wang, Lexin Li, Jingyi Jessica Li, Haiyan Huang

Abstract read
In one paragraph

Article in Statistical science : a review journal of the Institute of Mathematical Statistics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. A Matrix-VariateFrontiers in artificial intelligence · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Y X Rachel WangSchool of Mathematics and Statistics, University of Sydney, Australia.
Lexin LiDepartment of Biostatistics and Epidemiology, School of Public Health, University of California, Berkeley.
Jingyi Jessica LiDepartment of Statistics, University of California, Los Angeles.
Haiyan HuangDepartment of Statistics, University of California, Berkeley.

Funding

Neural and Biochemical Mechanisms of Cognitive AgingR01AG034570 · NIA · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI William J. Jagust · 2009 to 2026
$12.0M
Robust Identification and accurate quantification of RNA transcripts on a system wide scaleR01GM120507 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LI, JINGYI JESSICA · 2016 to 2021
$1.7M
New Statistical Methods for Multicenter Multimodal Longitudinal Neuroimaging AnalysisR01AG061303 · NIA · UNIVERSITY OF CALIFORNIA BERKELEY · PI LI, LEXIN · 2019 to 2022
$1.5M
NIA NIH HHS R01 AG034570NIA NIH HHS R01 AG061303NIGMS NIH HHS R01 GM120507
6 · The paper itself

Abstract

The rise of network data in many different domains has offered researchers new insight into the problem of modeling complex systems and propelled the development of numerous innovative statistical methodologies and computational tools. In this paper, we primarily focus on two types of biological networks, gene networks and brain networks, where statistical network modeling has found both fruitful and challenging applications. Unlike other network examples such as social networks where network edges can be directly observed, both gene and brain networks require careful estimation of edges using covariates as a first step. We provide a discussion on existing statistical and computational methods for edge esitimation and subsequent statistical inference problems in these two types of biological networks.

Indexed as

brain connectivity networksgene regulatory networksnetwork inferencenetwork reconstruction

Identifiers

PMID34305304
PMCPMC8296984

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.