Evidence map›Paper›PMID 34305277›Full record

ReviewMedical journal, Armed Forces India2021

Precision medicine: Uses and challenges.

Nardeep Naithani, Amar Tej Atal, T V S V G K Tilak, Biju Vasudevan, Pratibha Misra, Sharmila Sinha

Open access · greenAbstract readReview
In one paragraph

Review in Medical journal, Armed Forces India, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 59 citations in OpenAlex.

  1. Review
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  7. Article
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  10. Article
  11. Article
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  13. Navigating the Intersection of Technology and Depression Precision Medicine.Advances in experimental medicine and biology · 2024
    Review
  14. Review
  15. Article
  16. Precision Medicine in Type 2 Diabetes Mellitus: Utility and Limitations.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023
    Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Nardeep NaithaniDirector & Commandant, Armed Forces Medical College, Pune, India.
Amar Tej AtalAssociate Professor & Rheumatologist, Department of Internal Medicine, Armed Forces Medical College, Pune, India.
T V S V G K TilakProfessor & Medical Oncologist, Department of Internal Medicine, Armed Forces Medical College, Pune, India.
Biju VasudevanProfessor & Head, Department of Dermatology, Armed Forces Medical College, Pune, India.
Pratibha MisraProfessor & Head, Department of Biochemistry, Armed Forces Medical College, Pune, India.
Sharmila SinhaProfessor & Head, Department of Pharmacology, Armed Forces Medical College, Pune, India.
Armed Forces Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Precision medicine has brought in many changes to the practise of medicine. The omics-based development of biomarkers and pharmaco-omics-based drug development programmes are evidences for the advancement. However, the field where it has proved to be most useful is in the development of various modalities of treatment in oncology. Various drugs targeting vascular endothelial growth factor, epidermal growth factor, tyrosine kinase receptor and rat sarcoma mutations have come to the forefront proving to be beneficial in many cancers. Some of the classic drugs developed using this concept include trastuzumab, bevacizumab, cetuximab and panitumumab among others. Precision medicine has been put to best use in the COVID-19 pandemic through use of various biomarkers such as IL-6 and c-reactive protein in assessing severity of disease, for development of various therapies and also to judge efficacy of vaccines. Precision medicine is also finding its place in management of infectious diseases, chronic diseases such as asthma, connective tissue diseases, cardiovascular diseases, diabetes and obesity. India has also made its presence felt in the field by launching various initiatives such as the Indian genome project and Indian cancer genome atlas. Numerous challenges still exist to the future of precision medicine such as cost involved, ethics, security of the Big data, merger of various platforms to integrate data and also availability of trained manpower to manage the data and algorithms. This new age medicine is a big step forward for mankind and hopefully it will bring more benefits for both patients and the caregivers in the near future.

Indexed as

ChallengesEmergency MedicineOncologyPrecision medicine

Identifiers

PMID34305277
PMCPMC8282516
OpenAlexW3181321447

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.