Evidence map›Paper›PMID 34305256›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering2019

Predicting Cognitive Scores from Resting fMRI Data and Geometric Features of the Brain.

Anand A Joshi, Jian Li, Haleh Akrami, Richard M Leahy

Abstract read
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. A NETWORK-BASED APPROACH TO STUDY OF ADHD USING TENSOR DECOMPOSITION OF RESTING STATE FMRI DATA.Proceedings. IEEE International Symposium on Biomedical Imaging · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anand A JoshiSignal and Image Processing Institute, University of Southern California, Los Angeles, CA 90089.
Jian LiSignal and Image Processing Institute, University of Southern California, Los Angeles, CA 90089.
Haleh AkramiSignal and Image Processing Institute, University of Southern California, Los Angeles, CA 90089.
Richard M LeahySignal and Image Processing Institute, University of Southern California, Los Angeles, CA 90089.

Funding

BrainStorm: Highly Extensible Software for Advanced Electrophysiology and MEG/EEG ImagingR01EB026299 · NIBIB · UNIVERSITY OF SOUTHERN CALIFORNIA · PI LEAHY, RICHARD M · 2018 to 2025
$5.4M
Interactive software for semiautomated analysis of structural brain imagesR01NS074980 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LEAHY, RICHARD M, SHATTUCK, DAVID W · 2011 to 2021
$5.0M
Tools for Large-Scale Platform-Independent MEG Data AnalysisR01EB009048 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI HAMALAINEN, MATTI, LEAHY, RICHARD M · 2009 to 2016
$4.6M
A Brain Atlas for Mapping Connectivity in Focal EpilepsyR01NS089212 · NINDS · CLEVELAND CLINIC LERNER COM-CWRU · PI LEAHY, RICHARD M, MOSHER, JOHN COMPTON · 2015 to 2019
$2.7M
NIBIB NIH HHS R01 EB009048NIBIB NIH HHS R01 EB026299NINDS NIH HHS R01 NS074980NINDS NIH HHS R01 NS089212
6 · The paper itself

Abstract

Anatomical T1 weighted Magnetic Resonance Imaging (MRI) and functional magnetic resonance imaging collected during resting (rfMRI) are promising markers that offer insight into the structure and function of the human brain. The objective of this work is to explore the use of a deep learning neural network to predict cognitive performance scores for a population of normal controls and subjects with Attention Deficit Hyperactivity Disorder (ADHD). Specifically, we predict verbal and performance IQs and ADHD index from features derived from T1 and rfMRI imaging data. First, we processed the rfMRI and MRI data of subjects using the BrainSuite fMRI Processing (BFP) pipeline to perform anatomical and functional preprocessing. This produces for each subject fMRI and geometric (anatomical) features represented in a standardized grayordinate system. The geometric and functional cortical data corresponding to the two hemispheres were then transformed to 128×128 multichannel images and input to a convolutional component of the neural network. Subcortical data were presented in a standard vector form and inputted to a input layer of the network. The neural network was implemented in Python using the Keras library with a TensorFlow backend. Training was performed on 168 images with 90 images used for testing. We observed a high correlation between predicted and actual values of the indices tested: Performance IQ: 0.47; Verbal IQ: 0.41, ADHD: 0.57. Comparing these values to those from network trained on functional-only and structural-only data, we saw that rfMRI is more informative than MRI, but the two modalities are highly complementary in terms of predicting these indices.

Indexed as

ADHDbrainmachine learningresting fMRI

Identifiers

PMID34305256
PMCPMC8301598

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.