Evidence map›Paper›PMID 34304622›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2021

Longitudinal cortex-wide monitoring of cerebral hemodynamics and oxygen metabolism in awake mice using multi-parametric photoacoustic microscopy.

Vincent M Sciortino, Angela Tran, Naidi Sun, Rui Cao, Tao Sun, Yu-Yo Sun, Ping Yan, Fenghe Zhong, Yifeng Zhou, Chia-Yi Kuan and 2 more

Open access · greenAbstract read
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Biomedical optics express · 2022
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Vincent M SciortinoDepartment of Biomedical Engineering, 2358University of Virginia, University of Virginia, Charlottesville, VA, USA.ORCID 0000-0002-1116-732X
Angela TranDepartment of Biology, 2358University of Virginia, University of Virginia, Charlottesville, VA, USA.
Naidi SunDepartment of Biomedical Engineering, 2358University of Virginia, University of Virginia, Charlottesville, VA, USA.ORCID 0000-0002-2054-0392
Rui CaoDepartment of Biomedical Engineering, 2358University of Virginia, University of Virginia, Charlottesville, VA, USA.
Tao SunDepartment of Biomedical Engineering, 2358University of Virginia, University of Virginia, Charlottesville, VA, USA.
Yu-Yo SunDepartment of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO, USA.
Ping YanDepartment of Neuroscience, 2358University of Virginia, University of Virginia, Charlottesville, VA, USA.
Fenghe ZhongDepartment of Biomedical Engineering, 2358University of Virginia, University of Virginia, Charlottesville, VA, USA.
Yifeng ZhouDepartment of Biomedical Engineering, 2358University of Virginia, University of Virginia, Charlottesville, VA, USA.
Chia-Yi KuanDepartment of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO, USA.
Jin-Moo LeeDepartment of Neuroscience, 2358University of Virginia, University of Virginia, Charlottesville, VA, USA.
Song HuDepartment of Biomedical Engineering, 2358University of Virginia, University of Virginia, Charlottesville, VA, USA.
Washington University in St. Louis · USUniversity of Virginia · US

Funding

Plasticizing the Cortex to Enhance Stroke RecoveryR37NS110699 · NINDS · WASHINGTON UNIVERSITY · PI LEE, JIN-MOO · 2019 to 2025
$3.5M
Integrating TPM and PAM to examine the metabolic underpinning of neurovascular repair after strokeR01NS120481 · NINDS · WASHINGTON UNIVERSITY · PI HU, SONG, LEE, JIN-MOO · 2021 to 2025
$3.1M
Creatine Transporter Deficiency and Brain EnergeticsR01NS108763 · NINDS · UNIVERSITY OF VIRGINIA · PI KUAN, CHIA-YI · 2018 to 2022
$2.3M
INFLUENCE OF INTERHEMISPHERIC CONNECTIVITY ON RECOVERY AFTER FOCAL ISCHEMIAR01NS084028 · NINDS · WASHINGTON UNIVERSITY · PI LEE, JIN-MOO · 2013 to 2017
$2.2M
Crosstalk of Innate and Adaptive Immunity in Infection-Sensitized Neonatal HIER01NS095064 · NINDS · UNIVERSITY OF VIRGINIA · PI KUAN, CHIA-YI · 2016 to 2020
$1.7M
Photoacoustic Microscopy of the Awake Mouse BrainR01NS099261 · NINDS · WASHINGTON UNIVERSITY · PI HU, SONG · 2017 to 2021
$1.7M
NINDS NIH HHS R01 NS084028NINDS NIH HHS R01 NS095064NINDS NIH HHS R01 NS099261NINDS NIH HHS R01 NS108763NINDS NIH HHS R01 NS120481NINDS NIH HHS R37 NS110699
6 · The paper itself

Abstract

Multi-parametric photoacoustic microscopy (PAM) has emerged as a promising new technique for high-resolution quantification of hemodynamics and oxygen metabolism in the mouse brain. In this work, we have extended the scope of multi-parametric PAM to longitudinal, cortex-wide, awake-brain imaging with the use of a long-lifetime (24 weeks), wide-field (5 × 7 mm

Indexed as

Cerebrovascular CirculationMicroscopyPhotoacoustic TechniquesAnimalsBrainIschemic StrokeMaleMiceOxygenOxygencerebral vasculaturecranial windowlongitudinal imagingoxygen metabolismPhotoacoustic microscopy

Identifiers

PMID34304622
PMCPMC8669277
OpenAlexW3184941778

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.