ArticlePhilosophical transactions of the Royal Society of London. Series B, Biological sciences2021
Do male and female heterogamety really differ in expression regulation? Lack of global dosage balance in pygopodid geckos.
Article in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- A lizard is never late: Squamate genomics as a recent catalyst for understanding sex chromosome and microchromosome evolution.The Journal of heredity · 2023Pooled it
- Widespread male-female expression imbalance of X-linked genes across phrynosomatid lizards.Molecular biology and evolution · 2026Article
- Mixed Evidence that Dosage Sensitive Genes Drive Global Dosage Compensation in Flour Beetles.Genome biology and evolution · 2026Article
- Using a Handful of Transcriptomes to Detect Sex-Linked Markers and Develop Molecular Sexing Assays in a Species with Homomorphic Sex Chromosomes.Genome biology and evolution · 2024Article
- Heteromorphic ZZ/ZW sex chromosomes sharing gene content with mammalian XX/XY are conserved in Madagascan chameleons of the genus Furcifer.Scientific reports · 2024Article
- A lizard is never late: squamate genomics as a recent catalyst for understanding sex chromosome and microchromosome evolution.bioRxiv : the preprint server for biology · 2023Article
- Madagascar Leaf-Tail Geckos (Cells · 2023Article
- Identification of Iguania Ancestral Syntenic Blocks and Putative Sex Chromosomes in the Veiled Chameleon (International journal of molecular sciences · 2022Article
- Diversity of reptile sex chromosome evolution revealed by cytogenetic and linked-read sequencing.Zoological research · 2022Article
- Chromosome-Level Genome Assembly Reveals Dynamic Sex Chromosomes in Neotropical Leaf-Litter Geckos (Sphaerodactylidae: Sphaerodactylus).The Journal of heredity · 2022Article
- Review
- Sex chromosome evolution among amniotes: is the origin of sex chromosomes non-random?Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Article
- Expanding the classical paradigm: what we have learnt from vertebrates about sex chromosome evolution.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Review
- Whole-chromosome fusions in the karyotype evolution ofPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Article
- A brief review of vertebrate sex evolution with a pledge for integrative research: towards 'Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Review
- Preface.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Article
- Are Geckos Special in Sex Determination? Independently Evolved Differentiated ZZ/ZW Sex Chromosomes in Carphodactylid Geckos.Genome biology and evolution · 2021Article
- Independent Evolution of Sex Chromosomes in Eublepharid Geckos, A Lineage with Environmental and Genotypic Sex Determination.Life (Basel, Switzerland) · 2020Article
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Authors and funding
6 authors at 3 institutions in 7 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Differentiation of sex chromosomes is thought to have evolved with cessation of recombination and subsequent loss of genes from the degenerated partner (Y and W) of sex chromosomes, which in turn leads to imbalance of gene dosage between sexes. Based on work with traditional model species, theory suggests that unequal gene copy numbers lead to the evolution of mechanisms to counter this imbalance. Dosage compensation, or at least achieving dosage balance in expression of sex-linked genes between sexes, has largely been documented in lineages with male heterogamety (XX/XY sex determination), while ZZ/ZW systems are assumed to be usually associated with the lack of chromosome-wide gene dose regulatory mechanisms. Here, we document that although the pygopodid geckos evolved male heterogamety with a degenerated Y chromosome 32-72 Ma, one species in particular, Burton's legless lizard (
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