ReviewJournal of endocrinological investigation2021
Protocol for presurgical and anesthetic management of pheochromocytomas and sympathetic paragangliomas: a multidisciplinary approach.
Review in Journal of endocrinological investigation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Risk of complications after core needle biopsy in pheochromocytoma/paraganglioma.Endocrine-related cancer · 2023Pooled it
- Intracardiac paraganglioma in the left atrium in the context of a hereditary syndrome due to SDHD mutation: a case report.European heart journal. Case reports · 2026Article
- Successful treatment of a case of paraganglioma presenting Takotsubo syndrome.World journal of emergency medicine · 2026Article
- Preoperative inferior vena cava ultrasound for volume optimization in resection of functioning pheochromocytoma and paraganglioma: association with perioperative adverse outcomes in a prospective observational cohort.Frontiers in endocrinology · 2026Observational
- The Perioperative Biochemical and Clinical Considerations of Pheochromocytoma Management.International journal of molecular sciences · 2025Review
- Early readmission after adrenalectomy for pheochromocytoma. A retrospective study.Langenbeck's archives of surgery · 2025Article
- Perioperative Blood Pressure Management Recommendations in Pediatric Pheochromocytoma: A 10-Year Narrative Review.Kidney & blood pressure research · 2025Review
- Bladder paraganglioma: a 25-year systematic review unveils the benefits of early diagnosis in reducing surgical complications.Frontiers in surgery · 2025Article
- An unexpected retroperitoneal paraganglioma with hypertensive crisis during surgical resection: a case report and literature review.Frontiers in oncology · 2025Article
- Progress in surgical approaches and outcomes of patients with pheochromocytoma and paraganglioma.Best practice & research. Clinical endocrinology & metabolism · 2025Review
- Unexpected pheochromocytoma leading to cardiac arrest during the perioperative period: a case report and literature review.BMC anesthesiology · 2024Review
- Side-specific factors for intraoperative hemodynamic instability in laparoscopic adrenalectomy for pheochromocytoma: a comparative study.Surgical endoscopy · 2024Article
- Management of Abdominal Paraganglioma: A Single Center's Experience.Medicina (Kaunas, Lithuania) · 2024Article
- Management of rTTS associated with PGL using VA-ECMO and surgical resection: a case report.Frontiers in cardiovascular medicine · 2024Article
- Association between duration of phenoxybenzamine use and postoperative delirium in suspected adrenal pheochromocytoma: a retrospective cohort study.Frontiers in medicine · 2024Article
- Risk Factors for Perioperative Complications, Treatment Outcomes and Aggressive Behavior of the Tumor in Patients with Pheochromocytoma.Journal of the ASEAN Federation of Endocrine Societies · 2024Article
- Primary perioperative haemodynamic effects of ß-receptor blockade in patients with catecholamine-secreting tumours.BJA open · 2023Article
- Hemodynamic parameters in patients undergoing surgery for pheochromocytoma/paraganglioma: a retrospective study.World journal of surgical oncology · 2023Article
- Surgical strategies of complicated pheochromocytomas/paragangliomas and literature review.Frontiers in endocrinology · 2023Review
- Local recurrence and metastatic disease in pheochromocytomas and sympathetic paragangliomas.Frontiers in endocrinology · 2023Article
Corrections and comments
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Authors and funding
18 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo offer a practical guide for the presurgical and anesthetic management of pheochromocytomas and sympathetic paragangliomas (PGLs).
methodsThis protocol was based on a comprehensive review of the literature and on our own multidisciplinary team's experience from managing pheochromocytoma and sympathetic PGLs at a referral center.
resultsPatients with pheochromocytomas and sympathetic paragangliomas (PGLs) may develop potentially life-threatening complications, especially during surgical procedures. A complete biochemical, radiological, genetic, and cardiological assessment is recommended in the preoperative stage as it provides an evaluation of the risk of surgical complications and malignancy, allowing individualization of the presurgical treatment. Treatment with α-blockade and proper volume expansion in the preoperative stage significantly reduces the perioperative morbidity. During surgery, the anesthesiologist should look for a deep anesthetic level that inhibits the cardiovascular effects of catecholamines to minimize the risk of intraoperative complications.
conclusionsAn optimal presurgical evaluation of pheochromocytomas/ sympathetic PGL requires a multidisciplinary approach, including a complete hormonal, radiological, cardiac, genetic, and functioning evaluation in most cases. A proper preoperative evaluation in combination with strict blood pressure and heart rate control, and blood volume status optimization, will significantly reduce the risk of intraoperative and perioperative complications. In those patients who unfortunately develop intraoperative complications, the role of the anesthesiologist is essential since the selection of the appropriate management has a direct impact on morbimortality reduction.
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