Evidence map›Paper›PMID 34304292›Full record

Trial reportSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2022

Improvements in strength and agility measures of functional fitness following a telehealth-delivered home-based exercise intervention in endometrial cancer survivors.

Jessica S Gorzelitz, Stefanie Stoller, Erin Costanzo, Ronald Gangnon, Kelli Koltyn, Amy Trentham Dietz, Ryan J Spencer, Joanne Rash, Lisa Cadmus-Bertram

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
1.9field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Resistance training for fatigue in people with cancer.The Cochrane database of systematic reviews · 2024
    Pooled it
  3. Pooled it
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  11. Effect of Qigong exercise on quality of life and cortisol in patients with cancer: a non-randomized controlled trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
  12. Article
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  16. Efficacy of exercise interventions for women during and after gynaecological cancer treatment - a systematic scoping review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jessica S GorzelitzDepartment of Kinesiology, University of Wisconsin-Madison, 1300 University Ave, Bardeen 253A, Madison, WI, 53706, USA.
Stefanie StollerDepartment of Orthopaedic Surgery, Doctor of Physical Therapy Division, Duke University, Durham, NC, USA.
Erin CostanzoDepartment of Psychiatry, University of Wisconsin-Madison, Madison, WI, USA.
Ronald GangnonDepartments of Biostatistics & Medical Informatics, and Statistics, University of Wisconsin-Madison, Madison, WI, USA.
Kelli KoltynDepartment of Kinesiology, University of Wisconsin-Madison, 1300 University Ave, Bardeen 253A, Madison, WI, 53706, USA.
Amy Trentham DietzDepartment of Population Health Sciences, University of Wisconsin-Madison, Madison, WI, USA.
Ryan J SpencerDepartment of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of Wisconsin-Madison, Madison, WI, USA.
Joanne RashDepartment of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of Wisconsin-Madison, Madison, WI, USA.
Lisa Cadmus-BertramDepartment of Kinesiology, University of Wisconsin-Madison, 1300 University Ave, Bardeen 253A, Madison, WI, 53706, USA. lisa.bertram@wisc.edu.
University of Wisconsin–Madison · USDuke University · US

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Justine Yang Bruce · 1985 to 2026
$142.6M
University of Wisconsin Institute for Clinical and Translational ResearchUL1TR002373 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI ELIZABETH S BURNSIDE, Allan R. Brasier · 2017 to 2026
$75.9M
Feasibility Trial of Home-Based Strength Training in Endometrial Cancer SurvivorsR03CA230965 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI CADMUSBERTRAM, LISA ANNE · 2019 to 2020
$148k
American Cancer Society IRG-15-213-51Division of Cancer Epidemiology and Genetics, National Cancer Institute 1R03CA230965-01A1NCATS NIH HHS UL1 TR002373NCI NIH HHS P30 CA014520NCI NIH HHS R03 CA230965University of Wisconsin Carbone Cancer Center 2P30CA014520-44
6 · The paper itself

Abstract

purposeEndometrial cancer is strongly linked to obesity and inactivity; however, increased physical activity has important benefits even in the absence of weight loss. Resistance (strength) training can deliver these benefits; yet few women participate in resistance exercise. The purpose of this study was to describe both physiological and functional changes following a home-based strength training intervention.

methodsForty post-treatment endometrial cancer survivors within 5 years of diagnosis were enrolled in a pilot randomized trial, comparing twice-weekly home-based strength exercise to wait list control. Participants conducted the exercises twice per week for 10 supervised weeks with 5 weeks of follow-up. Measures included DXA-measured lean mass, functional fitness assessments, blood biomarkers, and quality of life outcomes.

resultsOn average, participants were 60.9 years old (SD = 8.7) with BMI of 39.9 kg/m

conclusionsHome-based muscle-strengthening exercise led to favorable and clinically relevant improvements in 3 of 7 physical function assessments. Physical function, body composition, blood biomarkers, and patient-reported outcomes were feasible to measure. These fitness improvements were observed over a relatively short time frame of 10 weeks.

Indexed as

Endometrial NeoplasmsTelemedicineExerciseExercise TherapyFemaleHand StrengthHumansMiddle AgedMuscle StrengthPhysical FitnessQuality of LifeSurvivorsInterventionQuality of lifeResistance exerciseStrength

Identifiers

PMID34304292
PMCPMC9362897
OpenAlexW3185598629

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.