ArticleIndian journal of ophthalmology2021
Correlation between systemic immune-inflammation index and routine hemogram-related inflammatory markers in the prognosis of retinopathy of prematurity.
Article in Indian journal of ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Significance of serum biomarkers in preterm infants screened for retinopathy of prematurity: a systematic review and meta-analysis.Eye (London, England) · 2025Pooled it
- The predictive role of early and late-stage inflammatory markers in the development of retinopathy of prematurity in discordant twins.Eye (London, England) · 2026Article
- Optimised multivariable prediction model to predict treatment requirement in preterm infants with retinopathy of prematurity.Eye (London, England) · 2026Article
- Predicting the treatment-requiring retinopathy of prematurity using birth weight, laboratory data and continuous peripheral capillary oxygen saturation monitoring.Japanese journal of ophthalmology · 2026Article
- Prognostic nutritional index in retinopathy of prematurity: a potential indicator of disease severity?International ophthalmology · 2025Article
- Development of a scoring model integrating inflammatory markers for predicting ROP in preterm neonates.International ophthalmology · 2025Article
- The Aggregate Index of Systemic Inflammation (AISI) is a Novel IgA Nephropathy Prognosis Predictor.Journal of inflammation research · 2025Article
- The association between the C-reactive protein-to-albumin-to-lymphocyte index and retinopathy: insights from a population-based study.Frontiers in nutrition · 2025Article
- The relationship between inflammatory markers and retinopathy of prematurity in extremely premature infants.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Article
- Abnormal Expression of Peripheral Blood Leukocyte Surface Markers in Retinopathy of Prematurity Patients.Journal of multidisciplinary healthcare · 2025Article
- Evaluation of peripheral blood inflammatory biomarkers in sickle cell disease with and without retinopathy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Article
- Predictive role of systemic immune-inflammation index and neutrophil/lymphocyte ratio values in infants with retinopathy of prematurity.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Article
- Predictive value of serum inflammatory markers in retinopathy of prematurity.Eye (London, England) · 2024Article
- Biofluid GPNMB/osteoactivin as a potential biomarker of ageing: A cross-sectional study.Heliyon · 2024Article
- Progress in the study of association between hematological indicators and retinopathy of prematurity (Review).Biomedical reports · 2024Review
- Relationship between lymphocytes and idiopathic macular hole.BMC ophthalmology · 2024Article
- Inflammatory and Hematologic Liver and Platelet (HALP) Scores in Hypothermia-Treated Hypoxic-Ischemic Encephalopathy (HIE).Children (Basel, Switzerland) · 2024Article
- Platelet count and retinopathy of prematurity, a systematic review and meta-analysis.Frontiers in pediatrics · 2024Review
- Complete blood count parameters as biomarkers of retinopathy of prematurity: a Portuguese multicenter study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Observational
- [Prognostic utility of inflammatory indexes in critically ill newborns].Revista medica del Instituto Mexicano del Seguro Social · 2023Observational
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5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To evaluate the prognostic potential of systemic inflammatory index in the course of retinopathy of prematurity (ROP). Methods: This is a retrospective case-control study. 303 infants with a gestational age of ≤35 weeks were screened with and without ROP at birth and 1 month after the birth of complete blood counts (CBC) were included in this study. Serum neutrophil-to-lymphocyte ratio (NLR), lymphocyte-to-monocyte ratio (LMR), platelet-to-lymphocyte (PLR), and systemic immune-inflammation index (SII) was calculated at birth and one month after. LMR was calculated by dividing the absolute lymphocyte count by the absolute monocyte count. NLR and PLR were determined by dividing the absolute neutrophil count or the absolute platelet count by the absolute lymphocyte count, respectively. The SII was calculated by the formula = neutrophilxplatelet/lymphocyte. All statistical analyses were performed using SPSS 22 (SPSS for Windows, version 22.0; SPSS, Inc. Chicago, IL, USA). Results: A total of 303 infants were included 145 with ROP and 158 without ROP. The NLR, LMR, PLR and SII values were 0.56 ± 1.17/0.51 ± 1.04 (P = 0.997), 13.7 ± 18/9.49 ± 13.1 (P = 0.014), 31.69 ± 68/24.1 ± 37.7 (P = 0.268), 131.42 ± 326/124.66 ± 267 (P = 0.935) in with ROP and without ROP infant at birth respectively. The NLR, LMR, PLR, and SII values were 0.68 ± 1.27/0.34 ± 0.99 (P = 0.001), 2.58 ± 6.01/2.46 ± 14.5 (P = 0.706), 47.5 ± 78.33/33.55 ± 42.4 (P = 0.035), and 253 ± 681/114 ± 345 (P = 0.001), respectively in with ROP and without ROP infant at 1 month after birth. Conclusion: The NLR, PLR, and SII seem an independent predictor of the development of ROP.
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