ArticleClinical biomechanics (Bristol, Avon)2021
Walking energetics and fatigue are associated with physical activity in people with knee osteoarthritis.
Article in Clinical biomechanics (Bristol, Avon), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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Who cites it
6 citing papers in PubMed, 9 citations in OpenAlex.
- Sensor-Based Monitoring of Knee Osteoarthritis Symptoms in Free-Living Settings: Scoping Review.Journal of medical Internet research · 2026Article
- Self-reported sedentary time and its influencing factors among patients with knee osteoarthritis: a cross-sectional survey.Scientific reports · 2025Article
- Individual joint contributions to forward propulsion during treadmill walking in women with hip osteoarthritis.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025Article
- Ischemic Preconditioning Improves Hip Abductor Strength and Power in Patients with Symptomatic Knee Osteoarthritis.Journal of musculoskeletal & neuronal interactions · 2024Article
- Association between sedentary behavior, physical activity, and osteoarthritis: results from NHANES 2007-2020 and Mendelian randomization analysis.Frontiers in public health · 2024Article
- Causal effect of physical activity and sedentary behaviors on the risk of osteoarthritis: a univariate and multivariate Mendelian randomization study.Scientific reports · 2023Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
backgroundAberrant biomechanics may influence osteoarthritis-associated physical activity limitations. Our purpose was to evaluate the association of walking energetics, fatigue, and fatigability on physical activity in people with knee osteoarthritis. We hypothesized that using increased energy for walking, experiencing more fatigue, or being more fatigable are associated with less activity, and that fatigue and fatigability mediate the relationships between walking energetics and physical activity.
methodsWe tested our hypothesis in 30 people with knee osteoarthritis (age 58 ± 9 years, 10 Male/20 Female). Physical activity was assessed using the University of California Los Angeles score. We used a six-minute walk test to predict VO
findingsGreater energy used during walking, fatigue, and fatigability were all associated with lower physical activity (rho = -0.585 to -0.379, P = 0.001 to 0.043). These associations persisted when incorporating pain into the models. Fatigue and fatigability mediated the associations between walking energetics and physical activity.
interpretationWalking energetics could be a useful target to promote physical activity in people with osteoarthritis. Further, the effect of walking energetics on physical activity may work through its impact on fatigability.
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Registered trials
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