Evidence map›Paper›PMID 34303780›Full record

ArticleNeuroscience2021

L5-6 Spinal Nerve Ligation-induced Neuropathy Changes the Location and Function of Ca

Kimberly Gomez, Alberto Vargas-Parada, Paz Duran, Alejandro Sandoval, Rodolfo Delgado-Lezama, Rajesh Khanna, Ricardo Felix

Open access · greenAbstract read
In one paragraph

Article in Neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Regulatory Action of Calcium and Calcium Channels in Pain Pathways.International journal of biological sciences · 2025
    Review
  6. Serotonin (5-HT)CNS neuroscience & therapeutics · 2024
    Article
  7. Article
  8. Ion channel long non-coding RNAs in neuropathic pain.Pflugers Archiv : European journal of physiology · 2022
    Review
  9. The role of Cdk5 in neurological disorders.Frontiers in cellular neuroscience · 2022
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Kimberly GomezDepartment of Physiology, Biophysics and Neuroscience, Centre for Research and Advanced Studies (Cinvestav), Mexico City, Mexico.
Alberto Vargas-ParadaDepartment of Physiology, Biophysics and Neuroscience, Centre for Research and Advanced Studies (Cinvestav), Mexico City, Mexico.
Paz DuranDepartment of Cell Biology, Cinvestav, Mexico City, Mexico.
Alejandro SandovalSchool of Medicine FES Iztacala, National Autonomous University of Mexico (UNAM), Tlalnepantla, Mexico.
Rodolfo Delgado-LezamaDepartment of Physiology, Biophysics and Neuroscience, Centre for Research and Advanced Studies (Cinvestav), Mexico City, Mexico.
Rajesh KhannaDepartment of Pharmacology, College of Medicine, The University of Arizona, Tucson, AZ, USA.
Ricardo FelixDepartment of Cell Biology, Cinvestav, Mexico City, Mexico. Electronic address: rfelix@cinvestav.mx.
Center for Research and Advanced Studies of the National Polytechnic Institute · MXUniversidad Nacional Autónoma de México · MXUniversity of Arizona · US

Funding

CRMP2, mitochondria, and Huntington’s diseaseR01NS098772 · NINDS · INDIANA UNIVERSITY INDIANAPOLIS · PI BRUSTOVETSKY, NICKOLAY, KHANNA, RAJESH · 2017 to 2021
$2.8M
Sentrin proteases, CRMP2 deSUMOylation, and Chronic PainR01NS120663 · NINDS · UNIVERSITY OF FLORIDA · PI KHANNA, RAJESH · 2020 to 2021
$2.6M
CRMP2, Nav1.7 sodium channel, and chronic painR01DA042852 · NIDA · UNIVERSITY OF ARIZONA · PI KHANNA, RAJESH · 2017 to 2021
$1.9M
NIDA NIH HHS R01 DA042852NINDS NIH HHS R01 NS098772NINDS NIH HHS R01 NS120663
6 · The paper itself

Abstract

Voltage-gated Ca

Indexed as

NeuralgiaSpinal NervesAction PotentialsAnimalsCyclin-Dependent Kinase 5Ganglia, SpinalHyperalgesiaNeurons, AfferentRatsRats, Sprague-DawleyCdk5 protein, ratCyclin-Dependent Kinase 5allodyniacalcium channelsCdk5neuropathic painolomoucinespinal nerve ligation

Identifiers

PMID34303780
PMCPMC8384716
OpenAlexW3185227692

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.